Antihypertensive efficacy and tolerability of different drug regimens in isolated systolic hypertension in the elderly

F Avanzini, C Alli, G Bettelli, R Corso… - European heart …, 1994 - academic.oup.com
The pharmacological treatment, mainly based on diuretics, of isolated systolic hypertension
(ISH) has recently been shown to reduce the risk of stroke and coronary heart disease in the …

Treatment of isolated systolic hypertension in the elderly: further evidence from the systolic hypertension in Europe (Syst-Eur) trial

JA Staessen, L Thijs, J Gąsowski, RH Fagard… - The American journal of …, 1998 - Elsevier
The Systolic Hypertension in Europe (Syst-Eur) study investigated whether antihypertensive
treatment could decrease the risk of cardiovascular complications in elderly patients with …

Treatment of isolated systolic hypertension in the elderly: the Syst-Eur trial

RH Fagard, JA Staessen - Clinical and Experimental Hypertension, 1999 - Taylor & Francis
The Syst-Eur study investigated whether active antihypertensive treatment could reduce
cardiovascular complications in elderly patients with isolated systolic hypertension …

[PDF][PDF] Syst-Eur-a multicenter trial on the treatment of isolated systolic hypertension in the elderly: first interim report

D Slovick - J Cardiovasc Pharmacol, 1992 - academia.edu
Syst-Eur is a multicenter placebo-controlled outcome trial designed by the European
Working Pany on High Blood Pressure in the Elderly to investigate the effect of …

Trials in isolated systolic hypertension: an update

B Waeber - Current hypertension reports, 2003 - Springer
Isolated systolic hypertension (ISH) has proved to be a powerful predisposing factor for
cardiovascular diseases in the elderly. Recent placebo-controlled interventional trials such …

Treatment strategies for isolated systolic hypertension in elderly patients

F Angeli, P Verdecchia, S Masnaghetti… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Hypertension is a major and modifiable risk factor for cardiovascular disease. Its
prevalence is rising as the result of population aging. Isolated systolic hypertension mostly …

Overview of the outcome trials in older patients with isolated systolic hypertension

JA Staessen, JG Wang, L Thijs, R Fagard - Journal of human …, 1999 - nature.com
Aims: Isolated systolic hypertension affects over 8 to 15% of all subjects older than 60 years.
In the elderly, systolic hypertension is the major modifiable cardiovascular risk factor. Three …

Treatment of isolated systolic hypertension in the elderly

D Duprez - Expert review of cardiovascular therapy, 2012 - Taylor & Francis
Systolic hypertension is a major health economy problem within our aging society.
Increased arterial stiffness is the vascular phenotype of systolic hypertension, especially of …

Clinical trials in isolated systolic hypertension

J Gasowski, JG Wang, JA Staessen - Current Hypertension Reports, 1999 - Springer
Isolated systolic hypertension affects 8% to 15% of all people older than 60 years of age. In
the elderly, systolic hypertension is the major modifiable cardiovascular risk factor. Three …

Hypertension as a function of age

GF Gensini, F Corradi - Italian Heart Journal: Official Journal of the …, 2000 - europepmc.org
Hypertension is one of the main risk factors for cerebrovascular disease (stroke), coronary
artery disease (acute myocardial infarction), congestive heart failure (both systolic and …