Novel strategies in selenium cancer chemoprevention research

C Ip, HE Ganther - Selenium in biology and human health, 1994 - Springer
Experimental studies with rodents indicate that selenium supplementation at levels above
the dietary requirement is capable of protecting against tumorigenesis induced by chemical …

Selenium in cancer prevention

MP Rayman, LC Clark - Trace Elements in Man and Animals 10, 2002 - Springer
The extensive experimental evidence, reviewed by Medina and Morrison (1988), and
Combs and Clark (1997), indicates that Se supplementation reduces the incidence of cancer …

Can dietary selenium modify cancer risk?

GF Combs Jr, LC Clark - Nutrition reviews, 1985 - agris.fao.org
Geographical studies of selenium status and cancer incidence indicate an inverse
relationship between selenium status and cancer mortality. This article examines studies …

Selenium in the prevention and treatment of hepatocellular carcinoma

AS Darvesh, A Bishayee - Anti-Cancer Agents in Medicinal …, 2010 - ingentaconnect.com
Hepatocellular carcinoma (HCC) happens to be one of the most lethal cancers in the world.
Even though most cases occur in the developing world, reported cases in Western Europe …

The need for speciation to realise the potential of selenium in disease prevention

S Moesgaard, R Morrill - Trace element speciation for …, 2001 - books.google.com
Speciation in its original meaning refers to the process of evolution by which diverse animal
or plant species evolve from common ancestors. In the context of selenium and cancer …

Selenium and cancer: biomarkers of selenium status and molecular action of selenium supplements

J Gromadzińska, E Reszka, K Bruzelius… - European journal of …, 2008 - Springer
Background The relationship between selenium and cancer involves many different aspects.
These include the forms of selenium present in the diet and in the body, their functions and …

Chemical versus food forms of selenium in cancer prevention

CD Davis, JW Finley - Functional Foods & Nutraceuticals in …, 2003 - Wiley Online Library
Selenium (Se) was discovered in 1817 by Berzelius who named it after Selene, the Greek
goddess of the moon. The history of biomedical research on Se is intriguing. Initially, Se was …

Selective distribution of selenium in colon parallels its antitumor activity

WP Banner, JJ DeCosse, QH Tan, MS Zedeck - Carcinogenesis, 1984 - academic.oup.com
Results of epidemiologic and experimental studies suggest that selenium can inhibit the
development of tumors. In rats, the administration of selenium decreases the incidence of …

Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice

SV Novoselov, DF Calvisi, VM Labunskyy, VM Factor… - Oncogene, 2005 - nature.com
The micronutrient element selenium (Se) has been shown to be effective in reducing the
incidence of cancer in animal models and human clinical trials. Selenoproteins and low …

Selenium-mediated inhibition of mammary carcinogenesis

C Ip - Biological trace element research, 1983 - Springer
Using the dimethylbenz (a) anthracene-induced mammary tumor model in rats, our studies
indicated that there was a dose-response relationship between dietary selenium …