Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines

M Pogribna, NA Koonce, A Mathew, B Word… - …, 2020 - Taylor & Francis
Nanoscale titanium dioxide (TiO2) is manufactured in wide scale, with a range of
applications in consumer products. Significant toxicity of TiO2 nanoparticles has, however …

Titanium dioxide nanoparticles induce size-dependent cytotoxicity and genomic DNA hypomethylation in human respiratory cells

Y Ma, Y Guo, S Wu, Z Lv, Q Zhang, Y Ke - RSC advances, 2017 - pubs.rsc.org
The widespread use of titanium dioxide nanoparticles (TiO2 NPs) is gradually increasing the
risk of exposure to these potentially hazardous materials. Although numerous health effects …

Epigenetic modulation upon exposure of lung fibroblasts to TiO2 and ZnO nanoparticles: alterations in DNA methylation

NA Patil, WN Gade, DD Deobagkar - International journal of …, 2016 - Taylor & Francis
Titanium dioxide (TiO2) and zinc oxide (ZnO) nanoparticles (NPs) are promising candidates
for numerous applications in consumer products. This will lead to increased human …

Effects of prenatal exposure to titanium dioxide nanoparticles on DNA methylation and gene expression profile in the mouse brain

K Tachibana, S Kawazoe, A Onoda… - Frontiers in …, 2021 - frontiersin.org
Background and Objectives: Titanium dioxide nanoparticles (TiO2-NP) are important
materials used in commercial practice. Reportedly, TiO2-NP exposure during pregnancy can …

The effect of nanomaterials on DNA methylation: A review

A Valente, L Vieira, MJ Silva, C Ventura - Nanomaterials, 2023 - mdpi.com
DNA methylation is an epigenetic mechanism that involves the addition of a methyl group to
a cytosine residue in CpG dinucleotides, which are particularly abundant in gene promoter …

Different effects of titanium dioxide nanoparticles instillation in young and adult mice on DNA methylation related with lung inflammation and fibrosis

Y Ma, Y Guo, H Ye, K Huang, Z Lv, Y Ke - Ecotoxicology and Environmental …, 2019 - Elsevier
Wide use of titanium dioxide nanoparticles (TiO 2 NPs) as white pigments induces
unintentionally release in environment which increases concerns about their adverse health …

Genotoxicity evaluation of titanium dioxide nanoparticles in vitro: a systematic review of the literature and meta-analysis

C Ling, H An, L Li, J Wang, T Lu, H Wang, Y Hu… - … Trace Element Research, 2021 - Springer
With the wide use of titanium dioxide nanoparticles (TiO 2-NPs), the genotoxicity of TiO 2-
NPs, which is a factor for safety assessment, has attracted people's attention. However, their …

Genotoxicity Evaluation of Titanium Dioxide Nanoparticles In Vivo and In Vitro: A Meta-Analysis

Y Cao, J Chen, Q Bian, J Ning, L Yong, T Ou, Y Song… - Toxics, 2023 - mdpi.com
Background: Recent studies have raised concerns about genotoxic effects associated with
titanium dioxide nanoparticles (TiO2 NPs), which are commonly used. This meta-analysis …

Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

ML Jugan, S Barillet, A Simon-Deckers… - …, 2012 - Taylor & Francis
Abstract Titanium dioxide nanoparticles (TiO2-NPs) are produced in large quantities, raising
concerns about their impact for human health. The aim of this study was to deeply …

Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice

B Trouiller, R Reliene, A Westbrook, P Solaimani… - Cancer research, 2009 - AACR
Titanium dioxide (TiO2) nanoparticles are manufactured worldwide in large quantities for
use in a wide range of applications including pigment and cosmetic manufacturing. Although …