Although amiodarone is regarded as a highly effective anti-arrhythmic agent, its use may
lead to alterations in thyroid gland function and/or thyroid hormone metabolism, partly …

Amiodarone (AM), a potent class III anti-arrhythmic drug, is an iodine-rich compound with a
structural resemblance to thyroid hormones triiodothyronine (T3) and thyroxine (T4). At the …

Amiodarone is a potent antiarrhythmic drug associated with thyroid dysfunction. Its high
iodine content causes inhibition of 5'-deiodinase activity. Most patients remain euthyroid …

Among the drugs affecting the thyroid gland, no drug has puzzled, and at the same time
fascinated, endocrinologists more than amiodarone. Amiodarone is a potent class III anti …

Amiodarone, a benzofuranic-derivative iodine-rich drug used mostly for tachyarrhythmias,
often causes changes in the peripheral metabolism of thyroid hormones mainly due to the …

Purpose: To review the literature on the effects of amiodarone on thyroid physiology and
management of amiodarone-induced thyroid disease. Data Sources: English-language …

Amiodarone is a benzofuranic-derivative iodine-rich drug widely used for the treatment of
tachyarrhythmias and, to a lesser extent, of ischemic heart disease. It often causes changes …

Amiodarone causes thyrotoxicosis in 3% of US patients who use it. Two types of amiodarone-
induced thyrotoxicosis are recognized, designated type 1 and type 2, based on whether or …

Diagnostic and therapeutic challenges abound in amiodarone-treated patients. Amiodarone
therapy results in perturbations in tests of thyroid function in euthyroid individuals as well as …

Amiodarone is an effective medication for the treatment of cardiac arrhythmias. Originally
developed for the treatment of angina, it is now the most frequently prescribed …