Characterization of a nuclear retention sequence within the 3′ region of the HIV-2 envelope gene

R Keller, L Montagnier, A Cordonnier - Virology, 1993 - Elsevier
During the phenotypic analysis of mutations in the HIV-2 envelope protein (gp140), we have
identified a mutant that expresses high levels of gp140 in the absence of the Rev protein …

Expression of human immunodeficiency virus 1 (HIV-1) envelope gene products transcribed from a heterologous promoter. Kinetics of HIV-1 envelope processing in …

C Bird, J Burke, PA Gleeson, J McCluskey - Journal of Biological Chemistry, 1990 - ASBMB
The expression of human immunodeficiency virus 1 (HIV-1) envelope glycoprotein products
was studied in cells transfected with env gene constructs transcribed from an SV40 …

The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

M Emerman, R Vazeux, K Peden - Cell, 1989 - cell.com
By in situ hybridization analysis and immunopmcipitatlonsfollowing transfection of COS
cells, we show that the Rev protein of the human immunodeficiency virus is necessary for …

Regulation of human immunodeficiency virus env expression by the rev gene product

ML Hammarskjöld, J Heimer, B Hammarskjöld… - Journal of …, 1989 - Am Soc Microbiol
A single simian virus 40 late replacement vector which expresses both the rev and envelope
(env) genes of human immunodeficiency virus was used to examine the mechanism …

U1 small nuclear RNA plays a direct role in the formation of a rev-regulated human immunodeficiency virus env mRNA that remains unspliced.

XB Lu, J Heimer, D Rekosh… - Proceedings of the …, 1990 - National Acad Sciences
rev-regulated expression of HIV-1 envelope proteins from a simian virus 40 late replacement
vector was found to be dependent on the presence of a 5'splice site in the env mRNA in …

Specific interaction of the human immunodeficiency virus Rev protein with a structured region in the env mRNA.

AW Cochrane, CH Chen… - Proceedings of the …, 1990 - National Acad Sciences
A region of potential complex secondary structure within the human immunodeficiency virus
env mRNA has been implicated in Rev-mediated export of viral structural mRNAs from the …

Identification of a novel splice acceptor in the HIV-1 genome: independent expression of the cytoplasmic tail of the envelope protein

B Berkhout, JLB Van Wamel - Archives of virology, 1996 - Springer
Multiple splicing sites exist in the RNA genome of the human immunodeficiency virus type 1
(HIV-1). In a screen for subgenomic forms of the HIV-1 genome that could be transferred to …

Rev-dependent expression of human immunodeficiency virus type 1 gp160 in Drosophila melanogaster cells

M Ivey-Hoyle, M Rosenberg - Molecular and cellular biology, 1990 - Am Soc Microbiol
Expression of the human immunodeficiency virus (HIV) structural proteins in mammalian
cells is regulated posttranscriptionally by the viral Rev protein. Rev has been shown to tnzns …

Regulation of HIV-1 envelope protein synthesis by Tat and Rev in 293 cells

V Natarajan, V Radjendirane, NP Salzman - Virology, 1993 - Elsevier
A plasmid expression vector (B2) with the HIV-1 envelope sequence downstream of the
adenovirus type 5 early region 3 promoter could direct the synthesis of envelope protein in …

Elements distinct from human immunodeficiency virus type 1 splice sites are responsible for the Rev dependence of env mRNA

G Nasioulas, AS Zolotukhin, C Tabernero… - Journal of …, 1994 - Am Soc Microbiol
In the absence of the viral regulatory protein Rev, the human immunodeficiency virus type 1
gag/pol and env mRNAs are inefficiently expressed, since nucleocytoplasmic transport …