Current perspectives on the genetic causes of neural tube defects

P De Marco, E Merello, S Mascelli, V Capra - neurogenetics, 2006 - Springer
Neural tube defects (NTDs) are a group of severe congenital abnormalities resulting from
the failure of neurulation. The pattern of inheritance of these complex defects is …

Toward understanding the genetic basis of neural tube defects

Z Kibar, V Capra, P Gros - Clinical genetics, 2007 - Wiley Online Library
Neural tube defects (NTDs) represent a common group of severe congenital malformations
that result from failure of neural tube closure during early development. Their etiology is …

Genetic basis of neural tube defects

AG Bassuk, Z Kibar - Seminars in pediatric neurology, 2009 - Elsevier
Neural tube defects (NTDs) represent a common group of severe congenital malformations
of the central nervous system. They result from failure of neural tube closure during early …

[HTML][HTML] A quest for genetic causes underlying signaling pathways associated with neural tube defects

S Rai, L Leydier, S Sharma, J Katwala… - Frontiers in Pediatrics, 2023 - frontiersin.org
Neural tube defects are dreadful congenital deformities of the nervous system that occur
owing to failure of normal neural tube closure. Genetic and non-genetic factors contribute to …

Neural tube defects—disorders of neurulation and related embryonic processes

AJ Copp, NDE Greene - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
Neural tube defects (NTDs) are severe congenital malformations affecting 1 in every 1000
pregnancies.'Open'NTDs result from failure of primary neurulation as seen in anencephaly …

Genetics of neural tube defects

J Gelineau-van Waes, RH Finnell - Seminars in Pediatric Neurology, 2001 - Elsevier
Neural tube defects (NTDs) are common congenital malformations that occur when the
embryonic neural tube fails to close properly during early development. Although …

Genetics of neural tube defects

JG Hall, F Solehdin - Mental retardation and developmental …, 1998 - Wiley Online Library
Neural tube defects are a complex, heterogeneous, and multifactorial group of disorders. In
humans it is estimated that 80% of neural tube defects are “multifactorial” and are influenced …

Genetics and development of neural tube defects

AJ Copp, NDE Greene - The Journal of Pathology: A Journal of …, 2010 - Wiley Online Library
Congenital defects of neural tube closure (neural tube defects; NTDs) are among the
commonest and most severe disorders of the fetus and newborn. Disturbance of any of the …

Neural tube defects

NDE Greene, AJ Copp - Annual review of neuroscience, 2014 - annualreviews.org
Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …

Folate and epigenetic mechanisms in neural tube development and defects

SV Meethal, KJ Hogan, CS Mayanil, BJ Iskandar - Child's nervous system, 2013 - Springer
Introduction Multiple genetic and epigenetic factors involved in central nervous system
(CNS) development influence the incidence of neural tube defects (NTDs). Discussion The …