Neural tube defects (NTDs) are common, often severe congenital malformations of the
central nervous system. Anencephaly and open spina bifida (myelomeningocele) arise from …

Purpose: Neural tube defects (NTDs), including spina bifida and anencephaly, are common
congenital malformations that occur when the neural tube fails to achieve proper closure …

The search for genetic determinants of human neural tube def... : Current Opinion in
Pediatrics The search for genetic determinants of human neural tube defects : Current …

Neural tube defects (NTDs) constitute a major health burden (0.5-2/1000 pregnancies
worldwide), and remain a preventable cause of still birth, neonatal, and infant death, or …

Neural tube closure (NTC) is crucial for proper development of the brain and spinal cord and
requires precise morphogenesis from a sheet of cells to an intact three‐dimensional …

The molecular requirements for neural tube closure are complex. This is illustrated by the
occurrence of neural tube defects (NTDs) in many genetic mouse mutants, which implicate a …

The number of mouse mutants and strains with neural tube defects (NTDs) now exceeds
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …

The human neural tube defects (NTD), anencephaly, spina bifida and craniorachischisis,
originate from a failure of the embryonic neural tube to close. Human NTD are relatively …

In recent years, use of animal models has resulted in acquisition of a significant amount of
new information regarding normal and abnormal neural tube development. Studies of …

Neural Tube Defects are a group of related but individual pathologies that are the most
common congenital anomalies of the Central Nervous System. The importance of this …