Biochemical and developmental pathways, mouse models, and positional evidence have
provided numerous candidate genes for the study of human neural tube defects. In a survey …

The embryonic development of mammalian neural tube defects - ScienceDirect Skip to
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Detailed investigations were made on 150 fetuses with neural tube defects (NTD). After
eliminating those with recognised causes, the rest were found to consist of fetuses with both …

Neural tube defects (NTD) in humans have been considered to have a multifactorial
aetiology, however the participating genes have not been identified. The curly–tail (ct) …

The vertebrate central nervous system is a hollow structure that develops first as a flat sheet
of cells and subsequently rolls into a tube during embryogenesis. Failure of this rolling …

Neural tube defects (NTDs), including spina bifida and anencephaly, represent the most
severe and common malformations of the central nervous system affecting 0.7–3 per 1000 …

The formation of the embryonic brain and spinal cord begins as the neural plate bends to
form the neural folds, which meet and adhere to close the neural tube. The neural ectoderm …

A genetic basis for neural tube defects (NTD) is rarely doubted, but the genes involved have
not yet been identified. This is partly due to a lack of suitable families on which to perform …

Genetic correlation of human neural tube defects (NTDs) with NTD genes identified in
mouse may unravel predisposing complex traits for assessment of individual risk and …

Neural tube defect disorders are developmental diseases that originate from an incomplete
closure of the neural tube during embryogenesis. Despite high prevalence—1 out of 3000 …