Neural tube defects (NTDs) are a group of malformations of the brain and spinal cord that
originate at various times during gestation. The most common NTDs are anencephaly and …

The neural tube is the first critically important structure that develops in the embryo. It serves
as the primordium of the central nervous system; therefore, the proper formation of the …

Background Multiple neural tube defects (MNTDs) are a rare occurrence. Although the
clinical incidence is small, MNTDs raise some interesting embryological queries. Aim This …

Epidemiological analysis of multiâ•’site closure failure of neural tube in humans Page 1
American Journal of Medical Genetics 66:64-68 (1996) Epidemiological Analysis of Multi-Site …

Neurulation, the early embryonic process of forming the presumptive brain and spinal cord,
is highly complex and involves hundreds of genes in multiple genetic pathways. Mice have …

Background Neural tube defects (NTD) are among the most common defects affecting 1:
1000 births. They are caused by a failure of neural tube closure during development. Their …

The mechanism (s) behind folate rescue of neural tube closure are not well understood. In
this study we show that maternal intake of folate prior to conception reverses the proliferation …

Neural tube defects (NTD) result from complex mechanisms between genes, nutrition and
environment. The identification of genetic predictors by genome exome sequencing and …

Neural tube defects are severe congenital malformations affecting around one in every 1000
pregnancies. An innovation in clinical management has come from the finding that closure of …

Neural tube defects (NTD) are one of the most common birth defects and are caused by both
environmental and genetic factors. The approach to identifying the genes predisposing to …