Interleukin-4 weakens host resistance to pulmonary and disseminated cryptococcal infection caused by combined treatment with interferon-γ-inducing cytokines
K Kawakami, MH Qureshi, T Zhang, Y Koguchi, Q Xie… - Cellular …, 1999 - Elsevier
We examined the role of interleukin (IL)-4 in host resistance against infection with
Cryptococcus neoformans. First, we examined the effects of a neutralizing anti-IL-4 …
Cryptococcus neoformans. First, we examined the effects of a neutralizing anti-IL-4 …
Role of Interleukin-4 in Resistance to Cryptococcus neoformans Infection
R Blackstock, JW Murphy - American journal of respiratory cell and …, 2004 - atsjournals.org
The role of interleukin (IL)-4 in cryptococcal disease was studied in IL-4 knockout (IL-4KO)
and wild-type (WT) mice infected with Cryptococcus neoformans isolates that vary widely in …
and wild-type (WT) mice infected with Cryptococcus neoformans isolates that vary widely in …
Combined effects of IL‐12 and IL‐18 on the clinical course and local cytokine production in murine pulmonary infection with Cryptococcus neoformans
MH Qureshi, T Zhang, Y Koguchi… - European journal of …, 1999 - Wiley Online Library
We reported recently that interleukin (IL)‐12 and IL‐18 synergistically increased the
fungicidal activity of mouse peritoneal exudate cells against Cryptococcus neoformans by …
fungicidal activity of mouse peritoneal exudate cells against Cryptococcus neoformans by …
Reduced host resistance and Th1 response to Cryptococcus neoformans in interleukin-18 deficient mice
K Kawakami, Y Koguchi, MH Qureshi… - FEMS microbiology …, 2000 - academic.oup.com
Abstract Using interleukin (IL)-18 deficient (IL-18−/−) mice, we examined the role of IL-18 in
the host resistance and Th1 response against infection with Cryptococcus neoformans …
the host resistance and Th1 response against infection with Cryptococcus neoformans …
Involvement of endogenously synthesized interleukin (IL)-18 in the protective effects of IL-12 against pulmonary infection with Cryptococcus neoformans in mice
K Kawakami, MH Qureshi, T Zhang… - FEMS Immunology & …, 2000 - academic.oup.com
We previously demonstrated that interleukin (IL)-12 protected mice against fatal pulmonary
infection with a highly virulent strain of Cryptococcus neoformans, which correlated well with …
infection with a highly virulent strain of Cryptococcus neoformans, which correlated well with …
IL‐12 protects mice against pulmonary and disseminated infection caused by Cryptococcus neoformans
K Kawakami, M Tohyama, Q Xie… - Clinical & Experimental …, 1996 - Wiley Online Library
We examined the role of IL‐12 in host resistance to Cryptococcus neoformans using a
murine model of pulmonary and disseminated infection. In this model, mice were infected …
murine model of pulmonary and disseminated infection. In this model, mice were infected …
The Gamma Interferon Receptor Is Required for the Protective Pulmonary Inflammatory Response to Cryptococcus neoformans
GH Chen, RA McDonald, JC Wells… - Infection and …, 2005 - Am Soc Microbiol
Mice with a null deletion mutation in the gamma interferon (IFN-γ) receptor gene were used
to study the role of IFN-γ responsiveness during experimental pulmonary cryptococcosis …
to study the role of IFN-γ responsiveness during experimental pulmonary cryptococcosis …
Contribution of interferon-γ in protecting mice during pulmonary and disseminated infection with Cryptococcus neoformans
K Kawakami, M Tohyama, K Teruya… - FEMS Immunology & …, 1996 - academic.oup.com
In the present study. the role of interferon-γ (IFN-γ) in the host resistance against
Cryptococcus neoformans was examined using a murine model of pulmonary and …
Cryptococcus neoformans was examined using a murine model of pulmonary and …
IL-12 and IFN-γ are required for initiating the protective Th1 response to pulmonary cryptococcosis in resistant CB-17 mice
KA Hoag, MF Lipscomb, AA Izzo… - American journal of …, 1997 - atsjournals.org
A murine model was used to assess the role of cytokines in initiating protective T-cell-
mediated immunity in the lung. A pulmonary infection was initiated by intratracheal …
mediated immunity in the lung. A pulmonary infection was initiated by intratracheal …
Chemokine responses and accumulation of inflammatory cells in the lungs of mice infected with highly virulent Cryptococcus neoformans: effects of interleukin-12
K Kawakami, K Shibuya, MH Qureshi… - FEMS Immunology & …, 1999 - academic.oup.com
We examined the mechanisms involved in the development of lung lesions after infection
with Cryptococcus neoformans by comparing the histopathological findings and chemokine …
with Cryptococcus neoformans by comparing the histopathological findings and chemokine …
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