The conjugative coupling protein TrwB is responsible for connecting the relaxosome to the
type IV secretion system during conjugative DNA transfer of plasmid R388. It is directly …

TrwB is an integral membrane protein linking the relaxosome to the DNA transport
apparatus in plasmid R388 conjugation. Native TrwB has been purified in monomeric and …

Bacterial conjugative systems code for an essential membrane protein that couples the
relaxosome to the DNA transport apparatus, called type IV coupling protein (T4CP). TrwB is …

Bacterial conjugation is an example of macromolecular trafficking between cells, based on
the translocation of single-stranded DNA across membranes through a type IV secretion …

Bacterial conjugation is an example of macromolecular trafficking between cells and
responsible for the spreading of antibiotic resistance among bacteria. It involves …

The transfer of DNA across membranes and between cells is a central biological process;
however, its molecular mechanism remains unknown. In prokaryotes, trans-membrane …

Conjugation is the most important mechanism for horizontal gene transfer and it is the main
responsible for the successful adaptation of bacteria to the environment. Conjugative …

Conjugative coupling proteins (CPs) are proposed to play a role in connecting the
relaxosome to a type IV secretion system (T4SS) during bacterial conjugation. Here we …

The stability of components of multiprotein complexes often relies on the presence of the
functional complex. To assess structural dependence among the components of the R388 …

Type IV secretory systems are transmembrane bacterial multiprotein complexes. They are
pivotal for conjugation, bacterial-induced plant tumour formation, toxin secretion and …