[HTML][HTML] Macrophage based drug delivery: Key challenges and strategies

Q Guo, ZM Qian - Bioactive Materials, 2024 - Elsevier
As a natural immune cell and antigen presenting cell, macrophages have been studied and
engineered to treat human diseases. Macrophages are well-suited for use as drug carriers …

Recent advances in macrophage-mediated drug delivery systems

T Liang, R Zhang, X Liu, Q Ding, S Wu… - International journal …, 2021 - Taylor & Francis
Macrophages have been extensively used in the development of drug delivery systems, as
they can prolong the circulation and release of drugs, extend their half-life, increase their …

Drug delivery to macrophages: challenges and opportunities

Y Pei, Y Yeo - Journal of Controlled Release, 2016 - Elsevier
Macrophages are prevalent in the body and have roles in almost every aspect of human
biology. They have often been considered a subject to avoid during drug delivery. However …

Drug delivery to macrophages: a review of targeting drugs and drug carriers to macrophages for inflammatory diseases

W He, N Kapate, CW Shields IV, S Mitragotri - Advanced drug delivery …, 2020 - Elsevier
Macrophages play a key role in defending against foreign pathogens, healing wounds, and
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …

Advancements in macrophage-targeted drug delivery for effective disease management

H Liu, H Lv, X Duan, Y Du, Y Tang… - International Journal of …, 2023 - Taylor & Francis
Macrophages play a crucial role in tissue homeostasis and the innate immune system. They
perform essential functions such as presenting antigens, regulating cytokines, and …

An overview on macrophage targeting: a promising approach

VD Vemuri, R Kushwaha, G Gowri… - Critical Reviews™ in …, 2023 - dl.begellhouse.com
Macrophages are immuno cells with high flexibility among hematopoietic system.
Macrophages are tangled with many diseases like chronic inflammatory, atherosclerosis …

Introduction to Pharmacology of Macrophages with Drug Delivery Perspective

M Gupta, A Pathak, YV Pathak, S Gupta - Macrophage Targeted Delivery …, 2022 - Springer
Ubiquitously present macrophages are an integral member of the innate immune system
and are crucially involved in host defense and homeostasis. They aid host defense by …

[HTML][HTML] Macrophage-related therapeutic strategies: regulation of phenotypic switching and construction of drug delivery systems

X Wang, Y Li, X Pu, G Liu, H Qin, W Wan… - Pharmacological …, 2023 - Elsevier
Macrophages, as highly phenotypic plastic immune cells, play diverse roles in different
pathological conditions. Changing and controlling the phenotypes of macrophages is …

“Zombie” Macrophages for Targeted Drug Delivery to Treat Acute Pneumonia

X Xu, CHT Kwong, J Li, J Wei… - ACS Applied Materials & …, 2023 - ACS Publications
A cell-based drug delivery system has emerged as a promising drug delivery platform. Due
to their innate inflammatory tropism, natural and engineered macrophages have exhibited …

[HTML][HTML] Harnessing macrophages for controlled-release drug delivery: lessons from microbes

JG Visser, ADP Van Staden, C Smith - Frontiers in pharmacology, 2019 - frontiersin.org
With the effectiveness of therapeutic agents ever decreasing and the increased incidence of
multi-drug resistant pathogens, there is a clear need for administration of more potent …