Neuroinflammation in Alzheimer's disease

F Zhang, L Jiang - Neuropsychiatric disease and treatment, 2015 - Taylor & Francis
Amyloid-β plaques and neurofibrillary tangles are the main neuropathological hallmarks in
Alzheimer's disease (AD), the most common cause of dementia in the elderly. However, it …

Neuroinflammation, Microglia and Implications for Anti‐Inflammatory Treatment in Alzheimer′ s Disease

DL Krause, N Müller - International journal of Alzheimer's …, 2010 - Wiley Online Library
Neuroinflammation has been implicated in the pathology of Alzheimer′ s disease (AD) for
decades. Still it has not been fully understood when and how inflammation arises in the …

Influence of microglia and astrocyte activation in the neuroinflammatory pathogenesis of Alzheimer's disease: Rational insights for the therapeutic approaches

MH Ahmad, M Fatima, AC Mondal - Journal of Clinical Neuroscience, 2019 - Elsevier
Abstract Alzheimer's disease (AD), the most common progressive neurodegenerative
disorder is characterized by the formation of extracellular amyloid plaques and intracellular …

[HTML][HTML] Glial cell-mediated neuroinflammation in Alzheimer's disease

NF Al-Ghraiybah, J Wang, AE Alkhalifa… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder; it is the most
common cause of dementia and has no treatment. It is characterized by two pathological …

Activation of microglia and astrocytes: a roadway to neuroinflammation and Alzheimer's disease

D Kaur, V Sharma, R Deshmukh - Inflammopharmacology, 2019 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease that is of high importance to the
neuroscience world, yet the complex pathogenicity is not fully understood. Inflammation is …

[HTML][HTML] Alzheimer's disease as an inflammatory disease

M Bolós, JR Perea, J Avila - Biomolecular concepts, 2017 - degruyter.com
Alzheimer's disease (AD) is a neurodegenerative condition characterized by the formation of
amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia …

Neuroinflammation in Alzheimer's disease: current progress in molecular signaling and therapeutics

S Thakur, R Dhapola, P Sarma, B Medhi, DHK Reddy - Inflammation, 2023 - Springer
Alzheimer's disease, a neurodegenerative disease with amyloid beta accumulation as a
major hallmark, has become a dire global health concern as there is a lack of clear …

Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?

F Leng, P Edison - Nature Reviews Neurology, 2021 - nature.com
Alzheimer disease (AD) is the most common form of neurodegenerative disease, estimated
to contribute 60–70% of all cases of dementia worldwide. According to the prevailing …

[HTML][HTML] Targeting neuroinflammation in Alzheimer's disease: From mechanisms to clinical applications

ZZ Si, CJ Zou, X Mei, XF Li, H Luo, Y Shen… - Neural regeneration …, 2023 - journals.lww.com
Alzheimer's disease is characterized by sustained neuroinflammation leading to memory
loss and cognitive decline. The past decade has witnessed tremendous efforts in …

[HTML][HTML] Cellular and molecular mediators of neuroinflammation in Alzheimer disease

SH Yang - International neurourology journal, 2019 - ncbi.nlm.nih.gov
Alzheimer disease (AD) is a neurodegenerative disorder characterized by the loss of
neuronal cells and the progressive decline of cognitive function. The major pathological …