Point-counterpoint: piperacillin-tazobactam should be used to treat infections with extended-spectrum-beta-lactamase-positive organisms

AN Schuetz, S Reyes, PD Tamma - Journal of clinical …, 2018 - Am Soc Microbiol
INTRODUCTION Beta-lactam/beta-lactamase inhibitor combination antimicrobials (BLBLIs)
are among the most controversial classes of antibiotic agents available for the treatment of …

[HTML][HTML] A novel framework to compare the effectiveness of β-lactamase inhibitors against extended-spectrum β-lactamase-producing Enterobacteriaceae

H Abodakpi, KT Chang, J Zhou, C Byerly… - Clinical Microbiology and …, 2019 - Elsevier
Objectives Extended-spectrum β-lactamases (ESBLs) present a serious challenge in the
treatment of Gram-negative bacterial infections. ESBLs mediate resistance to most β …

Antibiotic policy and prescribing strategies for therapy of extended‐spectrum β‐lactamase‐producing Enterobacteriaceae: the role of piperacillin–tazobactam

LR Peterson - Clinical Microbiology and Infection, 2008 - Wiley Online Library
Therapy of infections caused by extended‐spectrum β‐lactamase (ESBL)‐producing
bacteria with an antimicrobial to which they are resistant results in treatment failure, higher …

Outcomes analysis in patients with extended-spectrum beta-lactamase bacteremia empirically treated with piperacillin/tazobactam versus carbapenems

R John, P Colley, HL Nguyen… - Baylor University Medical …, 2019 - Taylor & Francis
Infections caused by extended-spectrum beta-lactamase (ESBL)-producing bacteria are
associated with worse outcomes and have limited treatment options. Carbapenems remain …

The use of noncarbapenem β-lactams for the treatment of extended-spectrum β-lactamase infections

PD Tamma, J Rodriguez-Baňo - Clinical Infectious Diseases, 2017 - academic.oup.com
The continued rise in infections caused by extended-spectrum β-lactamase (ESBL)–
producing pathogens is recognized globally as one of the most pressing concerns facing the …

[HTML][HTML] Antibiotic combination as empirical therapy for extended spectrum Beta-lactamase

Z Al-Muharrmi, A Rafay, A Balkhair… - Oman medical journal, 2008 - ncbi.nlm.nih.gov
Background extended spectrum β-lactamase (ESBL) producing gram negative bacilli are
becoming a growing problem worldwide with difficulties in designing a national formulary for …

Treatment options for extended-spectrum beta-lactamase (ESBL) and AmpC-producing bacteria

RG D'Angelo, JK Johnson, JT Bork… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Extended spectrum β-lactamases (ESBL) and AmpC β-lactamases are
increasing causes of resistance in many Gram-negative pathogens of common infections …

Management of infections caused by extended-spectrum β–lactamase-producing Enterobacteriaceae: current evidence and future prospects

CC Sheu, SY Lin, YT Chang, CY Lee… - Expert Review of Anti …, 2018 - Taylor & Francis
Introduction: The spread of extended-spectrum β–lactamase (ESBL)-producing
Enterobacteriaceae has become a major public health threat worldwide. Area covered: A …

Using β-lactam/β-lactamase inhibitors for infections due to extended-spectrum β-lactamase-producing Enterobacteriaceae to slow the emergence of carbapenem …

RR Watkins, S Deresinski - Expert Review of Anti-infective Therapy, 2017 - Taylor & Francis
Infections due to multidrug-resistant gram-negative bacteria are rapidly increasing in both
health care and community settings. In particular, extended-spectrum β-lactamase (ESBL) …

Can We Really Use ß-Lactam/ß-Lactam Inhibitor Combinations for the Treatment of Infections Caused by Extended-Spectrum ß-Lactamase–Producing Bacteria?

F Perez, RA Bonomo - Clinical Infectious Diseases, 2012 - academic.oup.com
In this issue a provocative study authored by Jesús Rodrıguez Bano and colleagues asserts
that the b-lactam/b-lactamase inhibitor (BLBLI) combinations piperacillin/tazobactam and …