Different Inhibitory Effects of Volatile Anesthetics on T- and L-type Voltage-dependent Ca2+Channels in Porcine Tracheal and Bronchial Smooth Muscles

M Yamakage, X Chen, N Tsujiguchi… - The Journal of the …, 2001 - pubs.asahq.org
Background The distal airway is more important in the regulation of airflow resistance than is
the proximal airway, and volatile anesthetics have a greater inhibitory effect on distal airway …

Anesthetic actions on cardiovascular control mechanisms in the central nervous system

WT Schmeling, NE Farber - Advances in pharmacology, 1994 - Elsevier
Publisher Summary This chapter delineates the effects of volatile anesthetics such as
halothane and isoflurane on vasomotor and preganglionic sympathetic neuronal responses …

Systemic vascular effects of isoflurane versus propofol anesthesia in dogs

YLJM Deryck, S Brimioulle, M Maggiorini… - Anesthesia & …, 1996 - journals.lww.com
Vascular effects of general anesthesia are usually described by changes in vascular
resistance, which assumes a linear pressure-flow relationship passing through the zero-flow …

Multiple Agents Potentiate α1-Adrenoceptor–induced Conduction Depression in Canine Cardiac Purkinje Fibers

AH Kulier, LA Turner, S Vodanovic… - The Journal of the …, 2000 - pubs.asahq.org
Background Halothane more so than isoflurane potentiates an alpha1-adrenoceptor (alpha1-
AR)-mediated action of epinephrine that abnormally slows conduction in Purkinje fibers and …

Region-specific and agent-specific dilation of intracerebral microvessels by volatile anesthetics in rat brain slices

NE Farber, CP Harkin, J Niedfeldt… - The Journal of the …, 1997 - pubs.asahq.org
Background Volatile anesthetics are potent cerebral vasodilators. Although the predominant
site of cerebrovascular resistance is attributed to intracerebral arterioles, no studies have …

Anesthesia-induced alteration of small vessel responses to norepinephrine

FN Miller, DL Wiegman - European Journal of Pharmacology, 1977 - Elsevier
Closed-circuit television microscopy was used to quantitate the in vivo response of small
arteries (≌ 100 μ m) and small veins (≌ 150 μ m) to topically applied norepinephrine in the …

Enflurane, halothane, and isoflurane attenuate contractile responses to exogenous and endogenous norepinephrine in isolated small mesenteric veins of the rabbit.

A Stadnicka, NM Flynn, ZJ Bosnjak, JP Kampine - Anesthesiology, 1993 - europepmc.org
Background Volatile anesthetics exert both direct and indirect (neurally mediated) effects to
produce splanchnic venodilation. These effects may result in clinically relevant …

Direct vasomotor effects of isoflurane in subepicardial resistance vessels from collateral-dependent and normal coronary circulation of pigs

KW Park, E Lowenstein, HB Dai, JJ Lopez… - The Journal of the …, 1996 - pubs.asahq.org
Background The purpose of the current investigation was to determine and compare the
direct effect of isoflurane on normal resistance coronary arteries and similarly sized coronary …

Endothelium-dependent circulatory control--a mechanism for the differing peripheral vascular effects of isoflurane versus halothane.

EP Greenblatt, AL Loeb, DE Longnecker - Anesthesiology, 1992 - europepmc.org
Several studies have suggested that halothane and isoflurane modify responses to
endothelium-dependent vasodilators, indicating that the differing circulatory effects of these …

Neural and endothelial control of the peripheral circulation—implications for anesthesia: part II, endothelium-mediated effects in the normal and diseased circulation

DF Stowe, TJ Ebert - Journal of cardiothoracic and vascular anesthesia, 1996 - Elsevier
HE CLASSIC view of neural-humoral control of the circulation held that postganglionic
sympathetic nerves in the perivascular space of vascular smooth muscle (VSM) release …