Background The site where volatile anesthetics inhibit endothelium-dependent, nitric oxide-
mediated vasodilation is unclear. To determine whether anesthetics could limit endothelium …

The time-dependent effects of catecholamines in combination with volatile anesthetics on
conduction velocity of canine Purkinje fibers were investigated to evaluate a controversial …

IMPLICATIONS: The present study suggests that the volatile anesthetic sevoflurane dose-
dependently impairs cerebrovascular autoregulation by mechanisms secondary to increase …

Background The extent to which isoflurane anesthesia alters systemic vascular regulation
has received considerable attention. In contrast, the pulmonary vascular effects of isoflurane …

Background Although previous studies have proposed that anesthetics may influence signal
transduction systems, their effects on the beta-adrenoceptor-mediated system have not been …

Abstract Atropine, homatropine, scopolamine, procaine, lidocaine and phentolamine
inhibited the contractile response of rabbit isolated pulmonary artery elicited by electrical …

The purpose of this review is to provide the anaesthetists with a comprehensive update on
the endothelial-cell control of local blood flow. This single cell layer was originally thought to …

This study examined the effect of sevoflurane on spontaneous renal sympathetic nerve
activity (RSNA), A delta-and C-fiber-mediated somatosympathetic reflexes, and …

Direct vasodilation of coronary resistance vessels by anesthetics may reduce coronary flow
reserve and interfere with myocardial flow-metabolism coupling. This study was performed …

To compare arteriolar versus venular smooth muscle sensitivity to myogenic and metabolic
inhibition during reduced blood pressure and flow, we measured the diameter of first-order …