An update on the pharmacological usage of curcumin: has it failed in the drug discovery pipeline?

F Olotu, C Agoni, O Soremekun… - Cell Biochemistry and …, 2020 - Springer
The pharmacological propensities of curcumin have been reported in a plethora of pre-
clinical and clinical studies. However, innate attributes account for extremely low oral …

Biomedical applications and bioavailability of curcumin—An updated overview

SI Sohn, A Priya, B Balasubramaniam… - Pharmaceutics, 2021 - mdpi.com
Curcumin, a yellow-colored molecule derived from the rhizome of Curcuma longa, has been
identified as the bioactive compound responsible for numerous pharmacological activities of …

Bioavailability of curcumin: problems and promises

P Anand, AB Kunnumakkara, RA Newman… - Molecular …, 2007 - ACS Publications
Curcumin, a polyphenolic compound derived from dietary spice turmeric, possesses diverse
pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and …

[HTML][HTML] Pharmacological mechanisms and clinical applications of curcumin: update

M Hao, Y Chu, J Lei, Z Yao, P Wang, Z Chen… - Aging and …, 2023 - ncbi.nlm.nih.gov
Curcumin, a well-known hydrophobic polyphenol extracted from the rhizomes of turmeric
(Curcuma longa L.), has attracted great interest in the last ten years due to its multiple …

Pharmacological and clinical properties of curcumin

CS Beevers, S Huang - Botanics: Targets and Therapy, 2011 - Taylor & Francis
The polyphenol natural product curcumin has been the subject of numerous studies over the
past decades, which have identified and characterized the compound's pharmacokinetic …

Multifaceted roles of curcumin: two sides of a coin!

SA Marathe, I Dasgupta, DP Gnanadhas… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Curcumin has been a front-line topic of mainstream scientific research for a
variety of diseases from cancer to Alzheimer's to infectious diseases. Curcumin suppresses …

Critical review on curcumin as a therapeutic agent: From traditional herbal medicine to an ideal therapeutic agent

MU Akbar, K Rehman, KM Zia, MI Qadir… - Critical Reviews™ in …, 2018 - dl.begellhouse.com
Traditionally, many natural medicinal plants have been used to treat a variety of diseases
since ancient times and are considered a potential source of phytochemicals for the …

A unifying perspective in blunting the limited oral bioavailability of curcumin: A succinct look

P Balakumar, T Alqahtani, A Alqahtani… - Current drug …, 2022 - ingentaconnect.com
Background: Curcumin is a polyphenolic compound derived from rhizomes of Curcuma
longa, the golden spice. Curcumin has drawn much attention in recent years of biomedical …

The clinical applications of curcumin: current state and the future

X Fan, C Zhang, D Liu, J Yan… - Current pharmaceutical …, 2013 - ingentaconnect.com
Curcumin is a natural polyphenol product derived from the rhizome of the Curcuma longa. In
vivo and in vitro studies have uncovered many important bioactivities of curcumin, such as …

Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …