Obesity and type 2 diabetes are associated with an increased risk of developing cancer and a worse prognosis; epidemiological and mechanistic evidence

D LeRoith, R Novosyadlyy, EJ Gallagher… - Experimental and …, 2008 - thieme-connect.com
Both obesity and Type 2 diabetes are independently associated with an increased risk of
developing cancer and an increased mortality. The etiology is yet to be determined but …

Obesity and diabetes epidemics: cancer repercussions

A Hjartåker, H Langseth, E Weiderpass - Innovative endocrinology of …, 2008 - Springer
The prevalence of overweight (body mass index, BMI, between 25 and 30 kg/m 2) and
obesity (BMI of 30 kg/m 2 or higher) is increasing rapidly worldwide, especially in …

Insulin, insulin resistance, obesity, and cancer

EJ Gallagher, D LeRoith - Current diabetes reports, 2010 - Springer
Epidemiologic studies have proposed a link between obesity, type 2 diabetes, and cancer.
The pathophysiologic mechanisms involved in the development of type 2 diabetes, namely …

Diabetes and cancer: two diseases with obesity as a common risk factor

SK Garg, H Maurer, K Reed… - Diabetes, Obesity and …, 2014 - Wiley Online Library
There is a growing body of evidence to support a connection between diabetes
(predominantly type 2), obesity and cancer. Multiple meta‐analyses of epidemiological data …

[HTML][HTML] Epidemiology and molecular mechanisms tying obesity, diabetes, and the metabolic syndrome with cancer

EJ Gallagher, D LeRoith - Diabetes care, 2013 - ncbi.nlm.nih.gov
It is well recognized that the world is witnessing an epidemic of obesity and type 2 diabetes
(T2D). Numerous studies have shown that both obesity and T2D are associated with an …

Obesity, type 2 diabetes, and cancer: the insulin and IGF connection

DH Cohen, D LeRoith - Endocrine-related cancer, 2012 - erc.bioscientifica.com
Epidemiological studies suggest a positive association between obesity and type 2 diabetes
mellitus (T2D) with the risk of cancer and cancer-related mortality. Insulin resistance …

Diabetes and cancer: A critical appraisal of the pathogenetic and therapeutic links

V Gristina, MG Cupri, M Torchio… - Biomedical …, 2015 - spandidos-publications.com
Diabetes and cancer represent two common, multifactorial, chronic and potentially fatal
diseases, not infrequently co‑diagnosed in the same patient. Epidemiological data …

[HTML][HTML] Obesity, insulin resistance and cancer risk

SH Jee, HJ Kim, J Lee - Yonsei Medical Journal, 2005 - ncbi.nlm.nih.gov
Obesity is a known cause of metabolic syndrome which includes Type II diabetes,
hypertension, and dyslipidemia. It is well documented that insulin resistance contributes to …

The relation of type 2 diabetes and cancer

HD Strickler, J Wylie-Rosett, T Rohan… - Diabetes technology …, 2001 - liebertpub.com
Increasing evidence indicates that individuals with type 2 diabetes (diabetes) are at elevated
risk for several common human malignancies, including cancers of the colon, breast …

Epidemiological bases and molecular mechanisms linking obesity, diabetes, and cancer

M Gutierrez-Salmeron, A Chocarro-Calvo… - … , Diabetes y Nutrición …, 2017 - Elsevier
The association between diabetes and cancer was hypothesized almost one century ago.
Today, a vast number of epidemiological studies support that obese and diabetic …