To cite this article: Hammad H, Lambrecht BN. Dendritic cells and airway epithelial cells at
the interface between innate and adaptive immune responses. Allergy 2011; 66: 579–587 …

The lung is continuously exposed to inhaled particles, microbes and harmless antigens to
which either immunity or tolerance is induced. Dendritic cells are mainly recognized for their …

The lung contains many subsets of dendritic cells that are distributed in various anatomical
compartments. In homeostatic conditions, a fine-tuned balance exists between plasmacytoid …

Allergic asthma is a chronic inflammatory disease of the airways characterized by airway
hyperresponsiveness (AHR), chronic airway inflammation, and excessive T helper (Th) type …

Highlights•Dendritic cells (DCs) are essential for inducing Th2 immunity to several
allergens.•Similar to other organs, lung DCs are a heterogeneous population of …

Allergic asthma is one of the most common chronic diseases in western society,
characterized by variable airway obstruction, mucus hypersecretion and infiltration of the …

Dendritic cells (DCs) and epithelial cells are the first cells to encounter inhaled allergens.
The response of these cell types to allergens is fundamentally different in asthmatics …

Dendritic cells (DCs) are the most efficient inducers of all immune responses, and are
capable of either inducing productive immunity or maintaining the state of tolerance to self …

Dendritic cells (DCs) are mainly known for their capacity to induce primary immune
responses. Here, we propose that DCs are similarly essential for controlling effector T-cell …

Although dendritic cells (DCs) play an important role in sensitization to inhaled allergens,
their function in ongoing T helper (Th) 2 cell–mediated eosinophilic airway inflammation …