Dendritic cells (DCs) are ideally placed in the airways and lungs to capture inhaled
allergens. Different subsets of DCs perform different tasks. Migratory conventional DCs …

Allergic asthma is characterized by airway hyperresponsiveness and inflammation and may
lead to airway remodeling in uncontrolled cases. Genetic predisposition to an atopic …

Since the first description of dendritic cells by Steinman and Cohn in 1973, this important cell
type has gained increasing attention. Over 4000 papers have been published on this topic …

The interaction between dendritic cells (DC) and naïve T cells is the first step in the evolution
of an immune response, either tolerogenic or inflammatory. Therefore, the status of DC …

BACKGROUND Airway dendritic cells (DC) play an important role in chronic allergic airway
inflammation in experimental animals, but a similar role for DC in human allergic asthma has …

BACKGROUND: Dendritic cells (DCs) are crucial for the induction of immunity and
tolerance. Despite an improved understanding of the DC-mediated control of TH1-biased …

Dendritic cells are crucial in determining the functional outcome of allergen encounter in the
lung. Antigen presentation by myeloid DCs leads to Th2 sensitization typical of allergic …

Dendritic cells (DC) have been shown to be responsible for the initiation and maintenance of
adaptive Th2 responses in asthma. It is increasingly clear that DC functions are strongly …

Lung dendritic cells bridge innate and adaptive immunity, integrating a variety of stimuli from
allergens, microbial colonisation, environmental pollution, and innate immune cells into a …

Dendritic cells (DCs) are known to play a central role in sensing the presence of foreign
antigens and infectious agents and in initiating appropriate immune responses. More …