Dendritic cells in human lung disease: recent advances

JW Upham, Y Xi - Chest, 2017 - Elsevier
Dendritic cells (DCs) are potent antigen-presenting cells. Because of their particular ability to
initiate and regulate cell mediated and humoral immune responses, there is considerable …

Accelerated airway dendritic cell maturation, trafficking, and elimination in a mouse model of asthma

K Vermaelen, R Pauwels - American journal of respiratory cell and …, 2003 - atsjournals.org
Pulmonary dendritic cells (DC) can induce both tolerogenic as well as inflammatory immune
responses in the lung. Conversely, little is known about the impact of ongoing airway …

Inhaled allergen‐driven CD1c up‐regulation and enhanced antigen uptake by activated human respiratory‐tract dendritic cells in atopic asthma

NE McCarthy, HA Jones, NA Marks… - Clinical & …, 2007 - Wiley Online Library
Background Dendritic cells (DC) mediate inflammation in rodent models of allergic airway
disease, but the role played by human respiratory‐tract DC (hRTDC) in atopic asthma …

[HTML][HTML] Between a cough and a wheeze: dendritic cells at the nexus of tobacco smoke-induced allergic airway sensitization

LJ Robays, T Maes, GF Joos, KY Vermaelen - Mucosal immunology, 2009 - Elsevier
Exposure to cigarette smoke represents a major risk factor for the development of asthma.
Enhanced sensitization toward allergens has been observed in humans and laboratory …

The interplay of dendritic cells, Th2 cells and regulatory T cells in asthma

H Kuipers, BN Lambrecht - Current opinion in immunology, 2004 - Elsevier
Dendritic cells are essential for Th2 differentiation of naïve CD4+ T cells in response to
aeroallergens, and in recent years it has been well established that these cells play a pivotal …

Dendritic cells in lung immunopathology

PC Cook, AS MacDonald - Seminars in immunopathology, 2016 - Springer
Dendritic cells (DCs) lie at the heart of the innate immune system, specialised at recognising
danger signals in many forms including foreign material, infection or tissue damage and …

[HTML][HTML] Division of labor between dendritic cell subsets of the lung

CH GeurtsvanKessel, BN Lambrecht - Mucosal immunology, 2008 - Elsevier
Dendritic cells (DCs) are a heterogenous population of antigen-presenting cells, of which
conventional DCs and plasmacytoid DCs are the main subsets. Like DC subsets in the …

Role of regulatory dendritic cells in allergy and asthma

O Akbari, DT Umetsu - Current Opinion in Allergy and Clinical …, 2004 - journals.lww.com
Role of regulatory dendritic cells in allergy and asthma : Current Opinion in Allergy and Clinical
Immunology Role of regulatory dendritic cells in allergy and asthma : Current Opinion in Allergy …

Persistent activation of dendritic cells after resolution of allergic airway inflammation breaks tolerance to inhaled allergens in mice

LS van Rijt, N Vos, M Willart, F Muskens… - American journal of …, 2011 - atsjournals.org
Rationale: Polysensitization of patients who are allergic is a common feature. The
underlying immunologic mechanism is not clear. The maturation status of dendritic cells …

Dendritic cells and the regulation of the allergic immune response

BN Lambrecht - Allergy, 2005 - Wiley Online Library
Studies in mouse models of asthma have revealed a critical role for airway dendritic cells in
the induction of Th2 sensitization to inhaled allergens. Under some conditions, subsets of …