Lung dendritic cells (DCs) bridge innate and adaptive immunity, and depending on context,
they also induce a Th1, Th2, or Th17 response to optimally clear infectious threats …

The respiratory tract is under constant bombardment from both innocuous and pathogenic
material. The decision of how to respond to these challenges is mediated by a specialized …

Dendritic cells (DCs) are antigen sampling sentinels of the peripheral tissue and specialists
for antigen capture, processing, and presentation to T cells as well as T-cell priming. By …

Allergic asthma is a chronic inflammatory disorder characterized by eosinophilia and T
helper type 2 (Th2) cell activation. However, little information is available on the …

This review updates the basic biology of lung DCs and their functions. Lung DCs have taken
center stage as cellular therapeutic targets in new vaccine strategies for the treatment of …

Background Myeloid (m) and plasmacytoid (p) dendritic cells (DC s) regulate immune
responses to allergens, whereas it remains unclear whether abnormal DC function …

Dendritic cells (DCs) are central to the integration of innate and adaptive immunity. In
contrast to B and T lymphocytes, DCs have retained many of the pattern recognition …

Pulmonary dendritic cells (DCs) constantly sample the tissue and traffic inhaled antigens to
the lung-draining lymph node where they normally orchestrate an appropriate immune …

The airway mucosal response to allergen in asthma involves influx of activated T helper type
2 cells and eosinophils, transient airflow obstruction, and airways hyperresponsiveness …

It is widely accepted that tissue dendritic cells (DC) function as immune sentinels by alerting
T cells to foreign antigen after delivering and presenting it in the draining lymph nodes. Over …