Dendritic cells are now recognized as the gatekeepers of the immune response, possessing
a unique potential for acquisition of antigens at extremely low exposure levels and for …

An emerging concept is that different types of dendritic cells (DCs) initiate different immune
outcomes, such as tolerance vs inflammation. In this study, we have characterized the DCs …

Airway mucosal dendritic cells (AMDC) and other airway APCs continuously sample inhaled
Ags and regulate the nature of any resulting T cell-mediated immune response. Although …

The aim of this study was to investigate whether dendritic cells (DCs) can induce
sensitization to aeroallergen in a mouse model of allergic asthma. Ovalbumin-pulsed (OVA …

BACKGROUND: In allergic rhinitis (AR) CD4+ TH2 lymphocytes control inflammation by
secreting TH2 cytokines, but little is known about how these cells are activated to cause …

Dendritic cells (DCs) are leukocytes that are emerging as chief orchestrators of immune
responses. The crucial task of DCs is the continuous surveillance of antigen-exposed sites …

Dendritic cells (DC) are potent antigen-presenting cells that are essential for initiating
adaptive immune responses. Residing within the airway mucosa, pulmonary DC continually …

Tolerance is the usual outcome of inhalation of harmless antigen, yet T helper (Th) type 2
cell sensitization to inhaled allergens induced by dendritic cells (DCs) is common in atopic …

BACKGROUND: Dendritic cells within the human respiratory mucosa (RTDCs) are proposed
to initiate immune responses to foreign antigens. Their capacity to polarize T-cell responses …

Dendritic cells (DCs) and macrophages (MΦs) are antigen-presenting phagocytic cells
found in many peripheral tissues of the human body, including the blood, lymph nodes, skin …