Allergic asthma is a chronic inflammatory disease of the airways that is driven by
maladaptive T helper 2 (Th2) and Th17 immune responses against harmless, airborne …

The function of lymphocytes in the immune system is to recognize foreign antigens and to
bring about their elimination directly or indirectly. For an antigen to be recognized by a T …

The dendritic cell in allergic airway diseases: a new player to the game Page 1 REVIEW The
dendritic cell in allergic airway diseases: a new player to the game BN LAMBRECHT Department …

A key rate-limiting step in the adaptive immune response at peripheral challenge sites is the
transmission of antigen signals to T cells in regional lymph nodes. Recent evidence …

Background Allergic asthma is a prevalent inflammatory disease of the airways caused by
dysregulated immune balance in the lungs with incompletely understood pathogenesis. The …

Dendritic cells (DCs) are crucial for mounting allergic airway inflammation, but it is unclear
which subset of DCs performs this task. By using CD64 and MAR-1 staining, we reliably …

Recent work from our laboratory has identified a network of constitutively class II MHC (Ia)
bearing dendritic cells (DC) within the epithelium of the conducting airways of laboratory …

Asthma is an inflammatory disease of the airways associated with a T helper (Th) 2
response. Such a response in the lungs requires complex interactions between innate cells …

Background Different subsets of dendritic cells (DCs), identified in mouse spleen by their
differential expression of CD8α, can induce different T‐helper (Th) responses after systemic …

Dendritic cells (DCs) are antigen (Ag)-presenting cells (APCs) characterized by a unique
capacity to stimulate naïve T cells and initiate primary immune responses. Recent studies …