Asthma is a prevalent chronic heterogeneous inflammatory disease of the airways, leading
to reversible airway obstruction, in which various inflammatory responses can be observed …

Intranasal (in) vaccination generates immunity across local, regional, and distant sites.
However, nasal dendritic cells (DCs), pivotal for the induction of in vaccine-induced immune …

Background Dendritic cells (DC) are the most potent antigen‐presenting cells (APC) and
stimulators of T cells. Dendritic cells are also likely to be essential for the initiation of allergic …

Cigarette smoking is associated with the development of allergic asthma. In mice, exposure
to cigarette smoke sensitizes the airways toward coinhaled OVA, leading to OVA-specific …

Professional antigen-presenting cells (APCs) constitute a heterogeneous leukocyte
population that controls T cell induction. Experimental animal studies have delineated the …

Background Dendritic cells (DC) are thought to play a key role in the initiation and
maintenance of T cell immunity to inhaled antigens. While the density of DC within the …

Airway dendritic cells (DCs) are held responsible for inducing sensitization to inhaled
antigen, leading to eosinophilic airway inflammation, typical of asthma. However, less …

Asthma is a common chronic lung disease that affects 300 million people worldwide. It
causes the airways of the lungs to swell and narrow due to inflammation (swelling and …

Conventional dendritic cells (DCs) are considered to be the prime initiators of airway allergy.
Yet, it remains unclear whether specific DC subsets are preferentially involved in allergic …

An increase in the tempo of local dendritic cell (DC)-mediated immune surveillance is a
recognized feature of the response to acute inflammation at airway mucosal surfaces, and …