Asthmatic bronchial epithelium activated by the proteolytic allergen Der p 1 increases selective dendritic cell recruitment

M Pichavant, AS Charbonnier, S Taront… - Journal of Allergy and …, 2005 - Elsevier
BACKGROUND: Airway dendritic cells (DCs) are crucial for allergen-induced sensitization
and inflammation in allergic asthma. After allergen challenge, an increased number of DCs …

Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice

BN Lambrecht, B Salomon, D Klatzmann… - The Journal of …, 1998 - journals.aai.org
Asthma is characterized by chronic eosinophilic inflammation of the airways, and allergen-
specific Th2 lymphocytes are thought to play a major role in the development and …

A major lung CD103 (αE)-β7 integrin-positive epithelial dendritic cell population expressing Langerin and tight junction proteins

SSJ Sung, SM Fu, CE Rose, F Gaskin… - The Journal of …, 2006 - journals.aai.org
Dendritic cells (DC) mediate airway Ag presentation and play key roles in asthma and
infections. Although DC subsets are known to perform different functions, their occurrence in …

Anatomical location determines the distribution and function of dendritic cells and other APCs in the respiratory tract

C von Garnier, L Filgueira, M Wikstrom… - The Journal of …, 2005 - journals.aai.org
APCs, including dendritic cells (DC), are central to Ag surveillance in the respiratory tract
(RT). Research in this area is dominated by mouse studies on purportedly representative RT …

Different roles for human lung dendritic cell subsets in pulmonary immune defense mechanisms

IK Demedts, KR Bracke, T Maes, GF Joos… - American journal of …, 2006 - atsjournals.org
Dendritic cells (DC) have a central role in the initiation of adequate immune responses. They
recognize pathogens by means of Toll-like receptors (TLR) and link innate to adaptive …

IL-10–treated dendritic cells decrease airway hyperresponsiveness and airway inflammation in mice

T Koya, H Matsuda, K Takeda, S Matsubara… - Journal of allergy and …, 2007 - Elsevier
BACKGROUND: IL-10 affects dendritic cell (DC) function, but the effects on airway
hyperresponsiveness (AHR) and inflammation are not defined. OBJECTIVE: We sought to …

[PDF][PDF] Immunology taught by lung dendritic cells.

C von Garnier, LP Nicod - Swiss medical weekly, 2009 - serval.unil.ch
Dendritic cells (DCs) are leukocytes specialised in the uptake, processing, and presentation
of antigen and fundamental in regulating both innate and adaptive immune functions. They …

Molecular regulation of Th2 immunity by dendritic cells

G Grunig, A Banz, R de Waal Malefyt - Pharmacology & therapeutics, 2005 - Elsevier
The interactions between dendritic cells (DCs) and T cells determine the fate of an immune
response to pathogenic microbes and to harmless allergens alike. The interactions between …

Characterization of dendritic cell populations in the respiratory tract

PG Holt, PA Stumbles - Journal of Aerosol Medicine, 2000 - liebertpub.com
Research in a variety of experimental animal species and in humans has identified dendritic
cells (DCs) as the principal resident antigen presenting cells in respiratory tract tissues. The …

Spatial interactions between dendritic cells and sensory nerves in allergic airway inflammation

TZ Veres, S Rochlitzer, M Shevchenko… - American journal of …, 2007 - atsjournals.org
Neuroimmune interactions play a critical role in the pathogenesis of asthma. Symptoms like
wheezing and cough have been attributed to neural dysregulation, whereas sensitization …