Effects of low level of methylmercury on proliferation of cortical progenitor cells

M Xu, C Yan, Y Tian, X Yuan, X Shen - Brain research, 2010 - Elsevier
Methylmercury (MeHg) is a potent environmental neurotoxin that shows toxicity to
developing central nervous system (CNS), causing brain damage in children even at low …

Low concentrations of methylmercury inhibit neural progenitor cell proliferation associated with up-regulation of glycogen synthase kinase 3β and subsequent …

M Fujimura, F Usuki - Toxicology and Applied Pharmacology, 2015 - Elsevier
Methylmercury (MeHg) is an environmental neurotoxicant. The developing nervous system
is susceptible to low concentrations of MeHg; however, the effect of MeHg on neural …

Inherited effects of low-dose exposure to methylmercury in neural stem cells

R Bose, N Onishchenko, K Edoff… - Toxicological …, 2012 - academic.oup.com
Methylmercury (MeHg) is an environmental contaminant with recognized neurotoxic effects,
particularly to the developing nervous system. In the present study, we show that nanomolar …

Low dose of methylmercury (MeHg) exposure induces caspase mediated-apoptosis in cultured neural progenitor cells

J Watanabe, T Nakamachi, H Ohtaki… - The Journal of …, 2013 - jstage.jst.go.jp
Methylmercury (MeHg) is an environmental pollutant known to cause neurobehavioY ral
defects, and it is especially toxic to the developing brain. In contrast to the adult, the …

High susceptibility of neural stem cells to methylmercury toxicity: effects on cell survival and neuronal differentiation

C Tamm, J Duckworth, O Hermanson… - Journal of …, 2006 - Wiley Online Library
Neural stem cells (NSCs) play an essential role in both the developing embryonic nervous
system through to adulthood where the capacity for self‐renewal may be important for …

Characterization of antioxidant protection of cultured neural progenitor cells (NPC) against methylmercury (MeHg) toxicity

J Watanabe, T Nakamachi, T Ogawa… - The Journal of …, 2009 - jstage.jst.go.jp
Methylmercury (MeHg) is an environmental pollutant known to cause neurobehavioral
defects and is especially toxic to the developing brain. With recent studies showing that fetal …

Gestational age and sex influence the susceptibility of human neural progenitor cells to low levels of MeHg

K Edoff, M Raciti, M Moors, E Sundström… - Neurotoxicity …, 2017 - Springer
The developing nervous system is highly susceptible to methylmercury (MeHg), a
widespread environmental neurotoxic contaminant. A wide range of morphological and …

The inhibitory mechanism of methylmercury on differentiation of human neuroblastoma cells

YJ Kim, YS Kim, MS Kim, JC Ryu - Toxicology, 2007 - Elsevier
Methylmercury (MeHg) is a ubiquitous environmental toxicant and shows neurotoxicity to
central nerve system (CNS) or neuronal cells. It has been known that MeHg has more …

Low‐dose methylmercury‐induced apoptosis and mitochondrial DNA mutation in human embryonic neural progenitor cells

X Wang, M Yan, L Zhao, Q Wu, C Wu… - Oxidative Medicine …, 2016 - Wiley Online Library
Methylmercury (MeHg) is a long‐lasting organic pollutant primarily found in the aquatic
environment. The developing brain is particularly sensitive to MeHg due to reduced …

Low level prenatal exposure to methylmercury disrupts neuronal migration in the developing rat cerebral cortex

BQ Guo, CH Yan, SZ Cai, XB Yuan, XM Shen - Toxicology, 2013 - Elsevier
We determined the effects of low-level prenatal MeHg exposure on neuronal migration in the
developing rat cerebral cortex using in utero electroporation. We used offspring rats born to …