Efficacy and safety of long-term amiodarone in treatment of cardiac arrhythmias: dosage experience

CI Haffajee, JC Love, JS Alpert, GK Asdourian… - American heart …, 1983 - Elsevier
The efficacy and safety of long-term oral amiodarone was assessed in 173 patients with
symptomatic tachyarrhythmias: 96 with life-threatening ventricular tachycardia and fibrillation …

Amiodarone therapy in symptomatic, sustained refractory atrial and ventricular tachyarrhythmias

PJ Podrid, B Lown - American Heart Journal, 1981 - Elsevier
Amiodarone was utilized in 70 patients with symptomatic, sustained refractory
tachyarrhythmias. Of these, 29 had atrial arrhythmia (20 recurrent atrial fibrillation and nine …

Long-term efficacy and toxicity of high-dose amiodarone therapy for ventricular tachycardia or ventricular fibrillation

F Morady, MJ Sauve, P Malone, EN Shen… - The American Journal of …, 1983 - Elsevier
Amiodarone was administered to 154 patients who had sustained, symptomatic ventricular
tachycardia (VT)(n= 118) or a cardiac arrest (n= 36) and who were refractory to conventional …

Clinical pharmacokinetics and efficacy of amiodarone for refractory tachyarrhythmias.

CI Haffajee, JC Love, AT Canada, LJ Lesko… - Circulation, 1983 - Am Heart Assoc
Using a high-pressure liquid chromatographic assay, we measured serum amiodarone
concentrations serially in 122 patients treated with amiodarone for 1.5-53 months (mean 9.3 …

Clinical efficacy of amiodarone as an antiarrhythmic agent

MB Rosenbaum, PA Chiale, MS Halpern… - The American Journal of …, 1976 - Elsevier
Amiodarone, administered orally in doses of 200 to 600 mg/day, was remarkably effective in
the treatment and prevention of a wide variety of atrial and ventricular arrhythmias. Total …

Efficacy of amiodarone for refractory supraventricular tachyarrhythmias

TB Graboys, PJ Podrid, B Lown - American heart journal, 1983 - Elsevier
Amiodarone was administered to 121 patients (82 males, 39 females; average age 59
years) with refractory atrial tachyarrhythmias. All patients had experienced recurrent atrial …

Long term efficacy and toxicity of amiodarone in the treatment of refractory cardiac arrhythmias.

R Primeau, A Agha, C Giorgi, M Shenasa… - The Canadian Journal …, 1989 - europepmc.org
Amiodarone has remarkable efficacy, but it also has a high incidence of severe side effects.
Nevertheless, it is extensively used. The findings of an amiodarone treatment follow-up …

Amiodarone: individualizing dosage with serum concentrations

HH Rotmensch, BN Swanson… - Pacing and Clinical …, 1983 - Wiley Online Library
The purpose of the present report is to review the available pharmacokinetic informaation on
amiodarone with an emphasis on our own experience in monitoring serum amiodarone …

Safety and efficacy of amiodarone: the low-dose perspective

PR Kowey, TD Friehling, RA Marinchak, AM Sulpizi… - Chest, 1988 - Elsevier
Amiodarone has been reported to be a remarkably safe and effective drug in the European
and South American experience but American investigators have published conflicting data …

High incidence of clinical and subclinical toxicity associated with amiodarone treatment of refractory tachyarrhythmias.

MI Anastasiou-Nana, JL Anderson… - … Canadian Journal of …, 1986 - europepmc.org
Amiodarone has been hailed as the most effective single antiarrhythmic drug for treatment of
refractory supraventricular and ventricular arrhythmias. However, questions continue to arise …