[HTML][HTML] Intra-articular injection of human synovium-derived mesenchymal stem cells in beagles with surgery-induced osteoarthritis

YS Kim, YI Kim, YG Koh - The Knee, 2021 - Elsevier
Background Recently, cell-based tissue engineering approaches using mesenchymal stem
cells (MSCs) have been used to treat osteoarthritis (OA). However, the efficacy of human …

[HTML][HTML] Not single but periodic injections of synovial mesenchymal stem cells maintain viable cells in knees and inhibit osteoarthritis progression in rats

N Ozeki, T Muneta, H Koga, Y Nakagawa… - Osteoarthritis and …, 2016 - Elsevier
Objective We investigated the effects of single or repetitive intra-articular injections of
synovial mesenchymal stem cells (MSCs) on a rat osteoarthritis (OA) model, and elucidated …

Multiple intra-articular injections of allogeneic bone marrow-derived stem cells potentially improve knee lesions resulting from surgically induced osteoarthritis: an …

EE Mahmoud, N Adachi, AS Mawas… - The bone & joint …, 2019 - boneandjoint.org.uk
Aim Mesenchymal stem cells (MSCs) have several properties that may support their use as
an early treatment option for osteoarthritis (OA). This study investigated the role of multiple …

The role of stem cells in osteoarthritis: an experimental study in rabbits

A Singh, SC Goel, KK Gupta, M Kumar… - Bone & joint …, 2014 - boneandjoint.org.uk
Introduction Osteoarthritis (OA) is a progressively debilitating disease that affects mostly
cartilage, with associated changes in the bone. The increasing incidence of OA and an …

Mesenchymal stem cell therapy in a rat model of osteoarthritis

GM Van Buul, M Siebelt, MJ Leijs, P Bos… - Osteoarthritis and …, 2012 - oarsijournal.com
Purpose: Mesenchymal stem cells (MSCs) are promising candidates for cartilage
regeneration and osteoarthritis (OA) therapies, due to their ability to form cartilage and to …

[PDF][PDF] Intra-articular injection of synovium-derived mesenchymal stem cells with hyaluronic acid can repair articular cartilage defects in a canine model

S Miki, M Takao, W Miyamoto, T Matsushita… - J Stem Cell Res …, 2015 - researchgate.net
Objective: The purpose of this study was to evaluate effectiveness of intra-articular injection
of synovium-derived mesenchymal stem cells (SMSCs) and hyaluronic acid (HA) for the …

Mesenchymal stem cells genetically engineered to express platelet-derived growth factor and heme oxygenase-1 ameliorate osteoarthritis in a canine model

J Oh, YS Son, WH Kim, OK Kwon, BJ Kang - Journal of Orthopaedic …, 2021 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are used for the treatment of
osteoarthritis (OA), and MSC genetic engineering is expected to enhance cartilage repair …

[HTML][HTML] Allogeneic mesenchymal stem cells in combination with hyaluronic acid for the treatment of osteoarthritis in rabbits

ER Chiang, HL Ma, JP Wang, CL Liu, TH Chen… - PloS one, 2016 - journals.plos.org
Mesenchymal stem cell (MSC)-based therapies may aid in the repair of articular cartilage
defects. The purpose of this study was to investigate the effects of intraarticular injection of …

Alleviation of osteoarthritis by intra-articular transplantation of circulating mesenchymal stem cells

W Lin, Z Yang, L Shi, H Wang, Q Pan, X Zhang… - Biochemical and …, 2022 - Elsevier
This study aimed to evaluate the efficacy of intra-articular delivery of peripheral blood
derived mesenchymal stromal cells (PB-MSCs) on the progression of trauma-induced …

Intra-articular mesenchymal stem cell injection for knee osteoarthritis: mechanisms and clinical evidence

P Wei, R Bao - International Journal of Molecular Sciences, 2022 - mdpi.com
Knee osteoarthritis presents higher incidences than other joints, with increased prevalence
during aging. It is a progressive process and may eventually lead to disability. Mesenchymal …