Adipose tissue comprises adipocytes and many other cell types that engage in dynamic
crosstalk in a highly innervated and vascularized tissue matrix. Although adipose tissue has …

Homeostatic regulation of adipose tissue is critical for the maintenance of energy balance
and whole-body metabolism. The peripheral nervous system provides bidirectional neural …

Brown and white adipose tissues are essential for maintenance of proper energy balance
and metabolic health. In order to function efficiently, these tissues require both endocrine …

During our study of the reversal of seasonal obesity in Siberian hamsters, we found an
interaction between receptors for the pineal hormone melatonin and the sympathetic …

The adipocyte-derived hormone leptin and the pancreatic β cell-derived hormone insulin
each function as afferent signals to the hypothalamus in an endocrine feedback loop that …

Adipose tissue remains a cryptic organ. The ubiquitous presence of adipocytes, the different
fat pads in distinct anatomical locations, the many different types of fat, in each case with …

Adipose tissue is a complex endocrine organ with an intricate role in whole body
homeostasis. Beyond storing energy, adipose tissue is fundamental in numerous processes …

Obesity is a risk factor for type 2 diabetes, dyslipidemia, and cardiovascular disease.
Dissection of the molecular mechanisms underlying obesity and its relationship to insulin …

Adipose tissues have a central role in energy homeostasis, as they secrete adipokines and
regulate energy storage and dissipation. Novel adipokines from white, brown and beige …

The difficulty in obtaining as well as maintaining weight loss, together with the impairment of
metabolic control in conditions like diabetes and cardiovascular disease, may represent …