Metastatic breast tumor cells display an epithelial–mesenchymal transition (EMT) that
increases cell motility, invasion, and dissemination. Although the transcription factor Twist1 …

Proinflammatory cytokines produced in the tumor microenvironment facilitate tumor
development and metastatic progression. In particular, TNF-α promotes cancer invasion and …

Twist1 is an epithelial–mesenchymal transition (EMT)-inducing transcription factor (TF) that
promotes cell migration and invasion. To determine the intrinsic role of Twist1 in EMT and …

Twist1, a basic helix–loop–helix transcription factor, promotes breast tumor cell epithelial–
mesenchymal transition (EMT), invasiveness, and metastasis. However, the mechanisms …

This article reviews the molecular structure, expression pattern, physiological function,
pathological roles and molecular mechanisms of Twist1 in development, genetic disease …

The heterogeneous breast cancers can be classified into different subtypes according to
their histopathological characteristics and molecular signatures. Foxa1 expression is linked …

Twist1 has a well-established role in inducing Epithelial-Mesenchymal Transition (EMT) to
promote tumor invasion and metastasis and can also inhibit apoptosis and confer stemness …

Metastasis, the foremost cause of mortality in cancer patients, is increasingly recognized as
a coordinated biological process. The multistep process of metastasis posts difficulty in …

The epithelial to mesenchymal transition (EMT) is a highly conserved cellular programme
that has an important role in normal embryogenesis and in cancer invasion and metastasis …

TWIST1 is a basic helix-loop-helix (bHLH) transcription factor which plays essential and
pivotal roles in multiple stages of embryonic development, and significantly contributes to …