The transcription factor TWIST1 is a basic helix-loop-helix protein that regulates epithelial-
mesenchymal transition (EMT) in early embryonic morphogenesis, cancer development, and …

TRIM28 regulates its target genes at both transcriptional and posttranscriptional levels. Here
we report that a TRIM28-TWIST1-EMT axis exists in breast cancer cells and TRIM28 …

TWIST, a basic helix-loop-helix transcription factor, has been recently reported to play an
important role in tumorigenesis of human cancer through converting the early stage tumors …

Aggressive cancer phenotypes are a manifestation of many different genetic alterations that
promote rapid proliferation and metastasis. In this study, we show that stable overexpression …

We uncovered a crucial role for the Aurora kinase A (AURKA)–Twist1 axis in promoting
epithelial-to-mesenchymal transition (EMT) and chemoresistance in pancreatic cancer …

TGF-β1 induces epithelial-mesenchymal transition (EMT) to stimulate cancer cell
progression, and TWIST1 is a critical regulator of EMT. In the present study, we determined …

Twist1 has been proposed to have oncogenic properties. Although Twist1 was reported to
interact with p300/CBP‐associated factor (PCAF) and to inhibit the functions of PCAF, it …

Stromal fibroblasts perform important roles in cancer development and progression.
Overexpression of Twist1, a basic helix-loop-helix transcription factor, is often associated …

In breast cancer, steroid receptor coactivator-1 (SRC-1) expression positively correlates with
HER2 expression and poor prognosis. In mouse mammary tumor virus–polyoma middle T …

TWIST1, an antiapoptotic and prometastatic transcription factor, is overexpressed in many
epithelial cancers including breast. Only little is known regarding the regulation of TWIST1 in …