Abstract The epithelial Na+ channel (ENaC) contributes to the clearance of fetal lung liquid.
In premature infants, low ENaC activity and low expression level of α‐ENaC have been …

Noninfective acute respiratory disease develops in approximately 1% of all newborn infants
and results in their admission to a critical care unit. Transient tachypnea of the newborn …

Objective. Active ion transport is critical to postnatal clearance of lung fluid. The importance
of epithelial sodium channel (ENaC) in this clearance has been demonstrated in animal …

Impaired lung epithelial Na+ channel (ENaC) activity at the time of birth results in respiratory
distress. To investigate potential mechanisms, the ontogeny and cellular distribution of the α …

At birth, the infant's lungs must be cleared of fetal lung fluid. This process is mediated
through the activation of airway epithelial sodium channels (ENaC). In animals, ENaC is …

At birth, lung fluid produced during fetal life must be cleared immediately and efficiently
before the first breath takes place, in order for infants to achieve a normal and successful …

The amiloride-sensitive epithelial sodium channel, ENaC, is thought to have a major role in
clearing fluid from the alveoli immediately after birth. ENaC-α knockout mice die soon after …

Background: Respiratory distress due to inadequate lung liquid clearance is a significant
problem in infants delivered late preterm or early term, especially by elective cesarean …

Background: The airway epithelial sodium channel (ENaC) is rate limiting for postnatal
alveolar fluid clearance. Increased lung water content is a feature of respiratory distress …

Introduction Lung fluid clearance is essential for successful postnatal pulmonary adaptation.
The epithelial sodium channel (ENaC) and Na‐K‐ATPase, induced by serum‐and …