Ex-vivo machine perfusion represents a superior organ preservation method over static cold
storage. There is still an urgent need for the optimization of the perfusion fluid and machine …

Background Abrupt temperature shift from hypothermia to normothermia incurred on
reperfusion of organ grafts has been delineated as a genuine factor contributing to …

Background: Liver transplant waiting list mortality is rising in the Western world because of a
shortage of donor organs. Current cold preservation limits the use of marginal donors by …

AIMS: The increasing shortage of donor organs has led to a focus on extended criteria
donors, including the non–heart-beating donor (NHBD). An optimal preservation method is …

Intestinal transplantation has become the therapy of choice for patients with intestinal failure
and life‐threatening complications from total parenteral nutrition. Results, however, remain …

In the face of a critical organ shortage in the Western world, various strategies are employed
to expand the donor pool for orthotopic liver transplantation (OLT). Among them is the …

Background. To minimize the ischemia-reperfusion injury that occurs to the liver with the
current method of preservation and transplantation, we have used an extracorporeal circuit …

Background Use of grafts from donors after cardiac death (DCD) would greatly contribute to
the expansion of the donor organ pool. However, this requires the development of novel …

One of the main problems in transplant surgery is the preservation of the organ during the
cold ischemic time. The interrupted blood supply triggers a cascade of biological …

The increased demand for organs has led to the increased usage of “higher risk” kidney and
liver grafts. These grafts from donation after circulatory death or expanded criteria donors …