Clinical administration of paclitaxel is hindered due to its poor solubility, which necessitates
the formulation of novel drug delivery systems to deliver such extreme hydrophobic drug. To …

This work shows a full spectrum of research on Vitamin E TPGS-emulsified Poly (d, l-lactic-
co-glycolic acid)(PLGA) nanoparticles (NPs) for paclitaxel formulation to improve its …

The aim of this study was to develop an alternative, more bio-available, better tolerated
paclitaxel nanosuspension (PTXNS) for intravenous injection in comparison with …

This work developed a system of nanoparticles of lipid monolayer shell and biodegradable
polymer core for controlled release of anticancer drugs with paclitaxel as a model drug, in …

Methoxy poly (ethylene glycol)-poly (lactide) copolymer (MPEG-PLA) was synthesized and
used to make nanoparticles by the nanoprecipitation method for clinical administration of …

Spray dry technique was applied to produce paclitaxel loaded microspheres of
biodegradable poly (lactic-co-glycolic acid)(PLGA) as an alternative delivery system …

Taxanes have established and proven effectivity against different types of cancers; in
particular breast cancers. However, the high hemolytic toxicity and hydrophobic nature of …

The purpose of this work was to develop Cremophor® EL-free nanoparticles (NPs) loaded
with Paclitaxel (PTX) in order to improve the drug iv pharmacokinetic profile and to evaluate …

Aim of present study was to develop a solid nanoemulsion preconcentrate of paclitaxel
(PAC) using oil [propylene glycol monocaprylate/glycerol monooleate, 4: 1 w/w], surfactant …

Docetaxel is a highly potent anticancer agent being used in a wide spectrum of cancer
types. There are important matters of concern regarding the drug's pharmacokinetics related …