In vitro and in vivo evaluation of actively targetable nanoparticles for paclitaxel delivery
Z Xu, W Gu, J Huang, H Sui, Z Zhou, Y Yang… - International journal of …, 2005 - Elsevier
The aim of the present work was to assess the merits of an actively targetable nanoparticles
(ATN), PEG-coated biodegradable polycyanoacrylate nanoparticles (PEG-nanoparticles) …
(ATN), PEG-coated biodegradable polycyanoacrylate nanoparticles (PEG-nanoparticles) …
Development, characterization and biological in vitro assays of paclitaxel-loaded PCL polymeric nanoparticles
JP Abriata, RC Turatti, MT Luiz, GL Raspantini… - Materials Science and …, 2019 - Elsevier
Adenocarcinoma is the most lethal gynecologic tumor and treatment usually consists in
surgery followed by chemotherapy. However, the chemotherapy benefits are eventually …
surgery followed by chemotherapy. However, the chemotherapy benefits are eventually …
Paclitaxel drug delivery systems: Focus on nanocrystals' surface modifications
Paclitaxel (PTX) is a chemotherapeutic agent that belongs to the taxane family and which
was approved to treat various kinds of cancers including breast cancer, ovarian cancer …
was approved to treat various kinds of cancers including breast cancer, ovarian cancer …
Nanoparticles of poly(D,L‐lactide)/methoxy poly(ethylene glycol)‐poly(D,L‐lactide) blends for controlled release of paclitaxel
Y Dong, SS Feng - … of Biomedical Materials Research Part A …, 2006 - Wiley Online Library
Paclitaxel is one of the best antineoplastic drugs found in nature in the past decades, which
has excellent therapeutic effects against a wide spectrum of cancers. Because of its high …
has excellent therapeutic effects against a wide spectrum of cancers. Because of its high …
Targeted delivery of paclitaxel using folate-decorated poly (lactide)–vitamin E TPGS nanoparticles
We synthesized nanoparticles (NPs) of the blend of two-component copolymers for targeted
chemotherapy with paclitaxel used as model drug. One component is poly (lactide)–d-α …
chemotherapy with paclitaxel used as model drug. One component is poly (lactide)–d-α …
Formulation and pharmacokinetic evaluation of a paclitaxel nanosuspension for intravenous delivery
Y Wang, X Li, L Wang, Y Xu, X Cheng… - International journal of …, 2011 - Taylor & Francis
Paclitaxel is a diterpenoid isolated from Taxus brevifolia. It is effective for various cancers,
especially ovarian and breast cancer. Due to its aqueous insolubility, it is administered …
especially ovarian and breast cancer. Due to its aqueous insolubility, it is administered …
A novel nanoparticle formulation for sustained paclitaxel delivery
WJ Trickler, AA Nagvekar, AK Dash - Aaps Pharmscitech, 2008 - Springer
Purpose To develop a novel nanoparticle drug delivery system consisting of chitosan and
glyceryl monooleate (GMO) for the delivery of a wide variety of therapeutics including …
glyceryl monooleate (GMO) for the delivery of a wide variety of therapeutics including …
Discriminated effects of thiolated chitosan-coated pMMA paclitaxel-loaded nanoparticles on different normal and cancer cell lines
The aim of the present work was to prepare and characterize poly (methyl methacrylate)
nanoparticles coated by chitosan–glutathione conjugate so as to encapsulate insoluble …
nanoparticles coated by chitosan–glutathione conjugate so as to encapsulate insoluble …
[HTML][HTML] Novel docetaxel chitosan-coated PLGA/PCL nanoparticles with magnified cytotoxicity and bioavailability
In the present study, docetaxel (DTX)-loaded poly (lactic-co-glycolic acid)(PLGA) and
polycaprolactone (PCL) nanoparticles were successfully prepared and coated with chitosan …
polycaprolactone (PCL) nanoparticles were successfully prepared and coated with chitosan …
Nanoscale drug delivery systems for cancer therapy using paclitaxel—A review of challenges and latest progressions
Paclitaxel (PTX) is an effective anticancer chemical with a broad spectrum that was primarily
obtained from a curative shrub, specifically the bark of Taxus brevifolia tree. It belongs to a …
obtained from a curative shrub, specifically the bark of Taxus brevifolia tree. It belongs to a …