PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy
Y Yoshizawa, Y Kono, K Ogawara, T Kimura… - International journal of …, 2011 - Elsevier
To find out potent paclitaxel (PTX) formulations for cancer chemotherapy, we formulated PTX
in O/W emulsion and liposome selected as candidates of nanocarriers for PTX. Surface …
in O/W emulsion and liposome selected as candidates of nanocarriers for PTX. Surface …
Biodegradable polymeric nanoparticles as the delivery carrier for drug
K Zhao, D Li, C Shi, X Ma, G Rong, H Kang… - Current Drug …, 2016 - ingentaconnect.com
Background: Drug research and development has entered into the new epoch of innovation
formulation, and the drug delivery system has been in the forefront of pharmaceutical …
formulation, and the drug delivery system has been in the forefront of pharmaceutical …
Preferential tumor accumulation and desirable interstitial penetration of poly (lactic-co-glycolic acid) nanoparticles with dual coating of chitosan oligosaccharide and …
Despite advances in polymeric nanoparticles (NPs) as effective delivery systems for
anticancer drugs, rapid clearance from blood and poor penetration capacity in …
anticancer drugs, rapid clearance from blood and poor penetration capacity in …
In-vivo efficacy of novel paclitaxel nanoparticles in paclitaxel-resistant human colorectal tumors
JM Koziara, TR Whisman, MT Tseng… - Journal of controlled …, 2006 - Elsevier
Colloidal carriers have been shown to improve tumor therapy by increased drug delivery
into tumor sites resulting directly from the enhanced permeability and retention effect (EPR) …
into tumor sites resulting directly from the enhanced permeability and retention effect (EPR) …
PLA/PLGA nanoparticles for sustained release of docetaxel
T Musumeci, CA Ventura, I Giannone, B Ruozi… - International journal of …, 2006 - Elsevier
This study investigates the potentiality of nanosphere colloidal suspensions as sustained
release systems for intravenous administration of docetaxel (DTX). Nanospheres were …
release systems for intravenous administration of docetaxel (DTX). Nanospheres were …
Controlled preparation and antitumor efficacy of vitamin E TPGS-functionalized PLGA nanoparticles for delivery of paclitaxel
G Wang, B Yu, Y Wu, B Huang, Y Yuan… - International journal of …, 2013 - Elsevier
Vitamin E TPGS-functionalized polymeric nanoparticles have been developed as a
promising drug delivery platform in recent years. Obtaining reproducible monodisperse …
promising drug delivery platform in recent years. Obtaining reproducible monodisperse …
Development of new lipid-based paclitaxel nanoparticles using sequential simplex optimization
X Dong, CA Mattingly, M Tseng, M Cho… - European journal of …, 2009 - Elsevier
The objective of these studies was to develop Cremophor-free lipid-based paclitaxel (PX)
nanoparticle formulations prepared from warm microemulsion precursors. To identify and …
nanoparticle formulations prepared from warm microemulsion precursors. To identify and …
Novel docetaxel-loaded nanoparticles based on PCL-Tween 80 copolymer for cancer treatment
Background The formulation of docetaxel available for clinical use (Taxotere®) contains a
high concentration of polysorbate 80 (Tween 80). After incorporation of Tween 80 into poly …
high concentration of polysorbate 80 (Tween 80). After incorporation of Tween 80 into poly …
Poly (lactide)–vitamin E derivative/montmorillonite nanoparticle formulations for the oral delivery of Docetaxel
Four systems of nanoparticles of biodegradable polymers were developed in this research
for oral delivery of anticancer drugs with Docetaxel used as a model drug, which include the …
for oral delivery of anticancer drugs with Docetaxel used as a model drug, which include the …
Poly (ethylene oxide)-modified poly (β-amino ester) nanoparticles as a pH-sensitive biodegradable system for paclitaxel delivery
The main objective of this study was to develop and characterize a pH-sensitive
biodegradable polymeric nanoparticulate system for tumor-selective paclitaxel delivery. A …
biodegradable polymeric nanoparticulate system for tumor-selective paclitaxel delivery. A …