Paclitaxel is one of the best antineoplastic drugs found from nature in the past decades,
which has been found effective against a wide spectrum of cancers including ovarian …

Purpose. We successfully manufactured nanoparticles of biodegradable polymers for
controlled release of paclitaxel. TPGS (d-α-tocopheryl polyethylene glycol 1000 succinate) …

The purpose of this study was to evaluate the effect of process (homogenization speed and
evaporation time) and formulation (aqueous/organic phase ratio, surfactant concentration …

Paclitaxel is one of the most effective antineoplastic drugs. Its current clinical administration
is formulated in Cremophor EL, which causes serious side effects. Nanoparticle (NP) …

Background Nanoparticles fabricated from the biodegradable and biocompatible polymer,
polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug …

This work evaluates the effects of paclitaxel loaded polymeric nanoparticles (NPs)
composed of poly (D, L-lactic-co-glycolic acid)(PLGA) with vitamin E TPGS as emulsifier for …

Paclitaxel (Taxol®) is an antineoplastic drug effective for various cancers especially ovarian
and breast cancer. Due to its high hydrophobicity, however, an adjuvant such as Cremophor …

The main objective of this study was to develop a polymeric drug delivery system for
paclitaxel, intended to be intravenously administered, capable of improving the therapeutic …

Paclitaxel (Taxol®) is one of the best antineoplastic drugs found from nature in the past
decades. Like many other anticancer drugs, there are difficulties in its clinical administration …

Polymeric nanoparticles (NPs) have great potential application in achieving targeted
delivery of anticancer drugs. Paclitaxel (PTX) loaded NPs were developed using …