Effects of telmisartan on cognition and regional cerebral blood flow in hypertensive patients with Alzheimer's disease

K Kume, H Hanyu, H Sakurai, Y Takada… - Geriatrics & …, 2012 - Wiley Online Library
Aim: Recent studies have shown that some antihypertensive medications are associated
with a significant reduction in the incidence of Alzheimer's disease (AD). However, it remains …

Effects of telmisartan on the level of Aβ1-42, interleukin-1β, tumor necrosis factor α and cognition in hypertensive patients with Alzheimer's disease

W Li, JW Zhang, F Lu, MM Ma, JQ Wang… - Zhonghua yi xue za …, 2012 - europepmc.org
Objective To explore the effects of telmisartan, an angiotensin II type 1 receptor blocker with
peroxisome proliferator-activated receptor γ-stimulating activity, on the levels of Aβ1-42 …

Effects of antihypertensive therapy on cognitive decline in Alzheimer's disease

E Duron, AS Rigaud, D Dubail… - American journal of …, 2009 - academic.oup.com
Background Therapeutic trials concerning the effect of antihypertensive therapy on cognition
have produced controversial findings. Our objective was to evaluate the impact of …

Safety and biomarker effects of candesartan in non-hypertensive adults with prodromal Alzheimer's disease

I Hajjar, M Okafor, L Wan, Z Yang, JA Nye… - Brain …, 2022 - academic.oup.com
Observational studies suggest that angiotensin receptor blockers in hypertensive adults are
associated with lower post-mortem indicators of Alzheimer's disease pathology …

The association between hypertension and dementia in the elderly

M Igase, K Kohara, T Miki - International journal of …, 2012 - Wiley Online Library
Hypertension (HT) and dementia are common disorders in the elderly. HT in the elderly is
associated with increased occurrence rates of dementia including Alzheimer′ s disease …

Effects of cholinesterase inhibitors appear greater in patients on established antihypertensive therapy

L Rozzini, B Vicini Chilovi, G Bellelli… - … journal of geriatric …, 2005 - Wiley Online Library
Introduction There is increasing evidence that hypertension may contribute to development
of dementia. Studies show that blood pressure lowering therapy might protect against …

Update on hypertension and Alzheimer's disease

I Skoog, D Gustafson - Neurological research, 2006 - Taylor & Francis
Several studies report that blood pressure is increased in victims of Alzheimer's disease
(AD) decades before the onset of the disease. Years before onset of Alzheimer's disease …

Associations of anti-hypertensive treatments with Alzheimer's disease, vascular dementia, and other dementias

NM Davies, PG Kehoe, Y Ben-Shlomo… - Journal of Alzheimer's …, 2011 - content.iospress.com
We investigated whether angiotensin II receptor blockers (ARBs) and angiotensin converting
enzyme inhibitors (ACE-Is) are more strongly associated with Alzheimer's disease (AD) …

Antihypertensive treatments, cognitive decline, and dementia

E Duron, O Hanon - Journal of Alzheimer's Disease, 2010 - content.iospress.com
Chronic hypertension is associated with an increased risk of both vascular dementia and
Alzheimer's disease (AD). In this context, the role of anti-hypertensive therapy for the …

Antihypertensive medication class and the risk of dementia and cognitive decline in older adults: a secondary analysis of the prospective HELIAD Cohort

I Liampas, A Hatzimanolis, V Siokas… - Journal of …, 2022 - content.iospress.com
Background: It is unclear whether the main antihypertensive medication classes (diuretics,
calcium channel blockers, betablockers, angiotensin converting enzyme inhibitors, and …