Ultraviolet radiation and melanomagenesis: from mechanism to immunotherapy
Melanoma is the deadliest form of skin cancer, and nearly 90% of melanomas are believed
to be caused by ultraviolet radiation (UVR), mainly from sunlight. UVR induces DNA …
to be caused by ultraviolet radiation (UVR), mainly from sunlight. UVR induces DNA …
Mechanisms and prevention of UV‐induced melanoma
A Sample, YY He - Photodermatology, photoimmunology & …, 2018 - Wiley Online Library
Melanoma is the deadliest form of skin cancer and its incidence is rising, creating a costly
and significant clinical problem. Exposure to ultraviolet (UV) radiation, namely UVA (315 …
and significant clinical problem. Exposure to ultraviolet (UV) radiation, namely UVA (315 …
Roles of UVA radiation and DNA damage responses in melanoma pathogenesis
AQ Khan, JB Travers, MG Kemp - Environmental and molecular …, 2018 - Wiley Online Library
The growing incidence of melanoma is a serious public health issue that merits a thorough
understanding of potential causative risk factors, which includes exposure to ultraviolet …
understanding of potential causative risk factors, which includes exposure to ultraviolet …
[HTML][HTML] Ultraviolet radiation-mediated development of cutaneous melanoma: An update
Ultraviolet (UV) light is absorbed by nucleic acids, proteins or other endogenous
chromophores, such as porphyrins, flavins and melanin, triggering biological processes in …
chromophores, such as porphyrins, flavins and melanin, triggering biological processes in …
Oxidative stress and genotoxicity in melanoma induction: impact on repair rather than formation of DNA damage?
T Douki - Photochemistry and Photobiology, 2020 - Wiley Online Library
Keratinocytes and melanocytes, two cutaneous cell types located within the epidermis, are
the origin of most skin cancers, namely carcinomas and melanomas. These two types of …
the origin of most skin cancers, namely carcinomas and melanomas. These two types of …
How sunlight causes melanoma
L Garibyan, DE Fisher - Current oncology reports, 2010 - Springer
The incidence of melanoma has continued to rise dramatically over the past few decades,
especially in young females. Due to the deadly nature of this disease, melanoma has …
especially in young females. Due to the deadly nature of this disease, melanoma has …
UVA Radiation, DNA damage, and melanoma
SG Jin, F Padron, GP Pfeifer - ACS omega, 2022 - ACS Publications
Melanoma is a lethal type of skin tumor that has been linked with sunlight exposure chiefly in
fair-skinned human populations. Wavelengths from the sun that can reach the earth's …
fair-skinned human populations. Wavelengths from the sun that can reach the earth's …
Stepping up melanocytes to the challenge of UV exposure
ZA Abdel‐Malek, AL Kadekaro… - Pigment cell & …, 2010 - Wiley Online Library
Exposure to solar ultraviolet radiation (UV) is the main etiological factor for skin cancer,
including melanoma. Cutaneous pigmentation, particularly eumelanin, afforded by …
including melanoma. Cutaneous pigmentation, particularly eumelanin, afforded by …
Ultraviolet radiation and cutaneous malignant melanoma
Recent years have seen a steady rise in the incidence of cutaneous malignant melanoma
worldwide. Although it is now appreciated that the key to understanding the process by …
worldwide. Although it is now appreciated that the key to understanding the process by …
Mechanism of UV-related carcinogenesis and its contribution to nevi/melanoma
A Brozyna, B Zbytek, J Granese… - Expert review of …, 2007 - Taylor & Francis
Melanoma constitutes 4–5% of all skin cancers but it contributes to 71–80% of skin cancer
deaths. UV light affects cell and tissue homeostasis owing to its damaging effects on DNA …
deaths. UV light affects cell and tissue homeostasis owing to its damaging effects on DNA …