Carbon nanotube-and asbestos-induced DNA and RNA methylation changes in bronchial epithelial cells

E Emerce, M Ghosh, D Öner, RC Duca… - Chemical Research …, 2019 - ACS Publications
Carbon nanotubes (CNTs) are nanoscale tube-shaped carbon materials used in many
industrial areas. Their fiber shape has caused concerns about their toxicity given their …

[HTML][HTML] Induction and recovery of CpG site specific methylation changes in human bronchial cells after long-term exposure to carbon nanotubes and asbestos

D Öner, M Ghosh, R Coorens, H Bové, M Moisse… - Environment …, 2020 - Elsevier
Introduction Inhalation of asbestos induces lung cancer via different cellular mechanisms.
Together with the increased production of carbon nanotubes (CNTs) grows the concern …

Differences in MWCNT-and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

D Öner, M Ghosh, H Bové, M Moisse, B Boeckx… - Particle and fibre …, 2018 - Springer
Background Subtle DNA methylation alterations mediated by carbon nanotubes (CNTs)
exposure might contribute to pathogenesis and disease susceptibility. It is known that both …

Multiwalled carbon nanotubes of varying size lead to DNA methylation changes that correspond to lung inflammation and injury in a mouse model

E Cole, JL Ray, S Bolten, RF Hamilton Jr… - Chemical Research …, 2019 - ACS Publications
Diversity in physicochemical properties of engineered multiwalled carbon nanotubes
(MWCNTs) increases the complexity involved in interpreting toxicity studies of these …

[HTML][HTML] Single-walled and multi-walled carbon nanotubes induce sequence-specific epigenetic alterations in 16 HBE cells

M Ghosh, D Öner, RC Duca, B Bekaert… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Recent studies have identified carbon nanotube (CNT)-induced epigenetic changes as one
of the key players in patho-physiological response. In the present study, we investigated …

Changes in DNA methylation induced by multi-walled carbon nanotube exposure in the workplace

M Ghosh, D Öner, K Poels, AM Tabish… - …, 2017 - Taylor & Francis
This study was designed to assess the epigenetic alterations in blood cells, induced by
occupational exposure to multi-wall carbon nanotubes (MWCNT). The study population …

Postchronic single-walled carbon nanotube exposure causes irreversible malignant transformation of human bronchial epithelial cells through DNA methylation …

J Wang, X Tian, J Zhang, L Tan, N Ouyang, B Jia… - ACS …, 2021 - ACS Publications
As environmental pollutants and possible carcinogens, carbon nanotubes (CNTs) have
recently been found to induce carcinogenesis and tumor metastasis after long-term …

[HTML][HTML] Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice

G Scala, MN Delaval, SP Mukherjee, A Federico… - Carbon, 2021 - Elsevier
Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) causes inflammation and
fibrosis. Our previous work has shown that industrially produced MWCNTs trigger specific …

Epigenetic effects of carbon nanotubes in human monocytic cells

D Öner, M Moisse, M Ghosh, RC Duca, K Poels… - …, 2017 - academic.oup.com
Carbon nanotubes (CNTs) are fibrous carbon-based nanomaterials with a potential to cause
carcinogenesis in humans. Alterations in DNA methylation on cytosine–phosphate …

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes

MI Sierra, L Rubio, GF Bayón, I Cobo… - …, 2017 - Taylor & Francis
Humans are increasingly exposed to nanoparticles and, although many of their
physiological effects have been described, the molecular mechanisms underlying them are …