Clinically important changes in individual and composite measures of rheumatoid arthritis activity: thresholds applicable in clinical trials
MM Ward, LC Guthrie, MI Alba - Annals of the rheumatic diseases, 2015 - ard.bmj.com
Objective Thresholds of minimal clinically important improvement (MCII) are needed to plan
and interpret clinical trials. We estimated MCIIs for the rheumatoid arthritis (RA) activity …
and interpret clinical trials. We estimated MCIIs for the rheumatoid arthritis (RA) activity …
The American College of Rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials
DT Felson, JJ Anderson, M Boers… - … : Official Journal of …, 1993 - Wiley Online Library
Objective. To develop a set of disease activity measures for use in rheumatoid arthritis (RA)
clinical trials, as well as to recommend specific methods for assessing each outcome …
clinical trials, as well as to recommend specific methods for assessing each outcome …
Determining the minimally important difference in the clinical disease activity index for improvement and worsening in early rheumatoid arthritis patients
JR Curtis, S Yang, L Chen, JE Pope… - Arthritis care & …, 2015 - Wiley Online Library
Objective Simplified measures to quantify rheumatoid arthritis (RA) disease activity are
increasingly used. The minimum clinically important differences (MCID) for some measures …
increasingly used. The minimum clinically important differences (MCID) for some measures …
Choosing a core set of disease activity measures for rheumatoid arthritis clinical trials.
DT Felson - The Journal of rheumatology, 1993 - europepmc.org
Rheumatoid arthritis (RA) clinical trials often include at least 10 measures of disease activity
(eg, tender and swollen joint counts, erythrocyte sedimentation rate, patient pain, grip …
(eg, tender and swollen joint counts, erythrocyte sedimentation rate, patient pain, grip …
[PDF][PDF] Patient's global assessment of disease activity: what are we measuring?
LHD van Tuyl, M Boers - Arthritis & Rheumatism, 2012 - academia.edu
There is a growing interest in the use of patientreported outcomes in rheumatoid arthritis
(RA) clinical trials as well as in clinical practice (1). More and more, patients actively …
(RA) clinical trials as well as in clinical practice (1). More and more, patients actively …
[HTML][HTML] Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score
Introduction Frequent assessments of rheumatoid arthritis (RA) disease activity allow timely
adaptation of therapy, which is essential in preventing disease progression. However …
adaptation of therapy, which is essential in preventing disease progression. However …
How much does Disease Activity Score in 28 joints ESR and CRP calculations underestimate disease activity compared with the Simplified Disease Activity Index?
R Fleischmann, D van der Heijde, AS Koenig… - Annals of the …, 2015 - ard.bmj.com
Objectives Disease Activity Score in 28 joints calculated with C-reactive protein (DAS28-
CRP) is used instead of erythrocyte sedimentation rate (DAS28-ESR) to assess rheumatoid …
CRP) is used instead of erythrocyte sedimentation rate (DAS28-ESR) to assess rheumatoid …
[HTML][HTML] Defining cut-off values for disease activity states and improvement scores for patient-reported outcomes: the example of the Rheumatoid Arthritis Impact of …
M Dougados, Y Brault, I Logeart… - Arthritis research & …, 2012 - Springer
Abstract Introduction The Rheumatoid Arthritis Impact of Disease (RAID) is a patient-
reported outcome measure evaluating the impact of rheumatoid arthritis (RA) on patient …
reported outcome measure evaluating the impact of rheumatoid arthritis (RA) on patient …
Clinical disease activity assessments in rheumatoid arthritis
F Salaffi, A Ciapetti - International Journal of Clinical …, 2013 - search.proquest.com
Over the years, the growing need to standardize methodologies in rheumatoid arthritis, to
improve the clinical management and evaluation of the effectiveness of treatments, has led …
improve the clinical management and evaluation of the effectiveness of treatments, has led …
The importance of reporting disease activity states in rheumatoid arthritis clinical trials
D Aletaha, J Funovits, JS Smolen - Arthritis & Rheumatism, 2008 - Wiley Online Library
Objective To compare the value of reporting treatment effects in rheumatoid arthritis (RA) as
relative change from baseline (eg, American College of Rheumatology [ACR] responder …
relative change from baseline (eg, American College of Rheumatology [ACR] responder …