Advanced nanomedicines for the treatment of inflammatory diseases

R Brusini, M Varna, P Couvreur - Advanced drug delivery reviews, 2020 - Elsevier
Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …

Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Nanomedicine delivers promising treatments for rheumatoid arthritis

LK Prasad, H O'Mary, Z Cui - Nanomedicine, 2015 - Taylor & Francis
An increased understanding in the pathophysiology of chronic inflammatory diseases, such
as rheumatoid arthritis, reveals that the diseased tissue and the increased presence of …

Drug delivery to macrophages: A review of nano-therapeutics targeted approach for inflammatory disorders and cancer

M Mukhtar, H Ali, N Ahmed, R Munir… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Macrophages are involved in the normal defense of the body; however, the
varying phenotypes of macrophages and imbalance in their ratio lead to the impairment of …

Monocytes and macrophages as nanomedicinal targets for improved diagnosis and treatment of disease

MA Lameijer, J Tang, M Nahrendorf… - Expert review of …, 2013 - Taylor & Francis
The important role of monocytes and macrophages in diseases like cancer and
atherosclerosis has started to get uncovered in the last decade. In addition, subsets of these …

Antioxidant nanotherapies for the treatment of inflammatory diseases

CW Li, LL Li, S Chen, JX Zhang, WL Lu - Frontiers in Bioengineering …, 2020 - frontiersin.org
Reactive oxygen species (ROS) are essential in regulating various physiological functions.
However, overproduction of ROS is implicated in the pathogenesis of various inflammatory …

Chronic inflammation's transformation to cancer: a nanotherapeutic paradigm

SS Sohrab, R Raj, A Nagar, S Hawthorne… - Molecules, 2023 - mdpi.com
The body's normal immune response against any invading pathogen that causes infection in
the body results in inflammation. The sudden transformation in inflammation leads to the rise …

Neutrophils and macrophages as targets for development of nanotherapeutics in inflammatory diseases

Y Su, J Gao, P Kaur, Z Wang - Pharmaceutics, 2020 - mdpi.com
Neutrophils and macrophages are major components of innate systems, playing central
roles in inflammation responses to infections and tissue injury. If they are out of control …

Chronic inflammatory diseases, anti-inflammatory agents and their delivery nanosystems

D Placha, J Jampilek - Pharmaceutics, 2021 - mdpi.com
Inflammatory diseases, whether caused by excessive stress on certain tissues/parts of the
body or arising from infections accompanying autoimmune or secondary diseases, have …

Nanoparticles targeting macrophages as potential clinical therapeutic agents against cancer and inflammation

G Hu, M Guo, J Xu, F Wu, J Fan, Q Huang… - Frontiers in …, 2019 - frontiersin.org
With the development of nanotechnology, significant progress has been made in the design,
and manufacture of nanoparticles (NPs) for use in clinical treatments. Recent increases in …