Summary Background Brugada syndrome (BrS) is a cardiac channelopathy that can result in
sudden cardiac death (SCD). SCN5A is the most frequent gene linked to BrS, but the …

Background Among rare channelopathies BrS patients are at high risk of sudden cardiac
death (SCD). SCN5A mutations are found in a quarter of patients. Other rare gene mutations …

Abstract Aims Brugada syndrome (BrS) is associated with a pronounced risk to develop
sudden cardiac death (SCD). Up to 21% of patients are related to mutations in SCN5A …

Abstract Background: Brugada syndrome (BrS), a disorder associated with characteristic
electrocardiogram precordial ST-segment elevation, predisposes afflicted patients to …

Brugada syndrome (BrS) is one of the major causes of sudden cardiac death in young
people, while the underlying mechanisms are not completely understood. Here, we …

Background Mutations in the cardiac sodium channel gene SCN5A cause Brugada
syndrome (BrS), an arrhythmic disorder that is a leading cause of sudden death and lacks …

Brugada syndrome (BrS) is an inherited and rare cardiac arrhythmogenic disease
associated with an increased risk of ventricular fibrillation and sudden cardiac death …

Brugada syndrome (BrS) is a rare cardiac rhythm disorder associated with sudden cardiac
death. Mutations in the sodium channel gene SCN5A are found in~ 20% of cases while …

Brugada syndrome is an inherited, rare cardiac arrhythmogenic disease, associated with
sudden cardiac death. It accounts for up to 20% of sudden deaths in patients without …

Brugada syndrome predisposes to sudden death due to disruption of normal cardiac ion
channel function, yet our understanding of the underlying cellular mechanisms is …