Recent advances in bio-orthogonal and dynamic crosslinking of biomimetic hydrogels
In recent years, dynamic,'click'hydrogels have been applied in numerous biomedical
applications. Owing to the mild, cytocompatible, and highly specific reaction kinetics, a …
applications. Owing to the mild, cytocompatible, and highly specific reaction kinetics, a …
Bioorthogonal strategies for engineering extracellular matrices
CM Madl, SC Heilshorn - Advanced Functional Materials, 2018 - Wiley Online Library
Hydrogels are commonly used as engineered extracellular matrix (ECM) mimics in
applications ranging from tissue engineering to in vitro disease models. Ideal mechanisms …
applications ranging from tissue engineering to in vitro disease models. Ideal mechanisms …
Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …
Supramolecular and dynamic covalent hydrogel scaffolds: from gelation chemistry to enhanced cell retention and cartilage regeneration
Supramolecular and dynamic covalent crosslinking (DCC) hydrogels not only display
unique physicochemical properties that can mimic the dynamic extracellular matrix (ECM) …
unique physicochemical properties that can mimic the dynamic extracellular matrix (ECM) …
Bioorthogonal click chemistry: an indispensable tool to create multifaceted cell culture scaffolds
MA Azagarsamy, KS Anseth - 2013 - ACS Publications
Over the past decade, bioorthogonal click chemistry has led the field of biomaterial science
into a new era of diversity and complexity by its extremely selective, versatile, and …
into a new era of diversity and complexity by its extremely selective, versatile, and …
Designing hydrogels for 3D cell culture using dynamic covalent crosslinking
Designing simple biomaterials to replicate the biochemical and mechanical properties of
tissues is an ongoing challenge in tissue engineering. For several decades, new …
tissues is an ongoing challenge in tissue engineering. For several decades, new …
Engineering multifunctional dynamic hydrogel for biomedical and tissue regenerative applications
Hydrogels have emerged in various biomedical applications, including tissue engineering
and medical devices, due to their ability to imitate the natural extracellular matrix (ECM) of …
and medical devices, due to their ability to imitate the natural extracellular matrix (ECM) of …
Tunable cross-linking and adhesion of gelatin hydrogels via bioorthogonal click chemistry
N Contessi Negrini, A Angelova Volponi… - ACS Biomaterials …, 2021 - ACS Publications
Engineering cytocompatible hydrogels with tunable physico-mechanical properties as a
biomimetic three-dimensional extracellular matrix (ECM) is fundamental to guide cell …
biomimetic three-dimensional extracellular matrix (ECM) is fundamental to guide cell …
Tuning hydrogels by mixing dynamic cross‐linkers: enabling cell‐instructive hydrogels and advanced bioinks
FLC Morgan, J Fernández‐Pérez… - Advanced …, 2022 - Wiley Online Library
Rational design of hydrogels that balance processability and extracellular matrix (ECM)
biomimicry remains a challenge for tissue engineering and biofabrication. Hydrogels …
biomimicry remains a challenge for tissue engineering and biofabrication. Hydrogels …
Design strategies of stimuli-responsive supramolecular hydrogels relying on structural analyses and cell-mimicking approaches
H Shigemitsu, I Hamachi - Accounts of Chemical Research, 2017 - ACS Publications
Conspectus Stimuli-responsive hydrogels are intriguing biomaterials useful for
spatiotemporal controlled release of drugs, cells, and biological cues, cell engineering for …
spatiotemporal controlled release of drugs, cells, and biological cues, cell engineering for …