Broad and differential animal angiotensin-converting enzyme 2 receptor usage by SARS-CoV-2

X Zhao, D Chen, R Szabla, M Zheng, G Li, P Du… - Journal of …, 2020 - Am Soc Microbiol
The COVID-19 pandemic has caused an unprecedented global public health and economic
crisis. The origin and emergence of its causal agent, SARS-CoV-2, in the human population …

Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2

Y Liu, G Hu, Y Wang, W Ren, X Zhao… - Proceedings of the …, 2021 - National Acad Sciences
The pandemic of COVID-19, caused by SARS-CoV-2, is a major global health threat.
Epidemiological studies suggest that bats (Rhinolophus affinis) are the natural zoonotic …

[HTML][HTML] The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins

C Conceicao, N Thakur, S Human, JT Kelly… - PLoS …, 2020 - journals.plos.org
SARS Coronavirus 2 (SARS-CoV-2) emerged in late 2019, leading to the Coronavirus
Disease 2019 (COVID-19) pandemic that continues to cause significant global mortality in …

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

J Damas, GM Hughes, KC Keough… - Proceedings of the …, 2020 - National Acad Sciences
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of COVID-19. The main receptor of SARS-CoV-2, angiotensin I converting enzyme …

SARS-CoV-2 and three related coronaviruses utilize multiple ACE2 orthologs and are potently blocked by an improved ACE2-Ig

Y Li, H Wang, X Tang, S Fang, D Ma, C Du… - Journal of …, 2020 - Am Soc Microbiol
The ongoing coronavirus disease 2019 (COVID-19) pandemic has caused> 20 million
infections and> 750,000 deaths. Severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Advances in research on ACE2 as a receptor for 2019-nCoV

J Wu, W Deng, S Li, X Yang - Cellular and Molecular Life Sciences, 2021 - Springer
Currently, a novel coronavirus (SARS-CoV-2, also called 2019-nCoV) has triggered
pandemic Coronavirus Disease 2019 (COVID-19), an acute infectious respiratory disease …

Comparison of severe acute respiratory syndrome coronavirus 2 spike protein binding to ACE2 receptors from human, pets, farm animals, and putative intermediate …

X Zhai, J Sun, Z Yan, J Zhang, J Zhao, Z Zhao… - Journal of …, 2020 - Am Soc Microbiol
The emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), resulted in a pandemic. Here, we used X-ray structures of human ACE2 …

Increasing host cellular receptor—angiotensin‐converting enzyme 2 expression by coronavirus may facilitate 2019‐nCoV (or SARS‐CoV‐2) infection

MW Zhuang, Y Cheng, J Zhang… - Journal of medical …, 2020 - Wiley Online Library
The ongoing outbreak of a new coronavirus (2019‐nCoV, or severe acute respiratory
syndrome coronavirus 2 [SARS‐CoV‐2]) has caused an epidemic of the acute respiratory …

[HTML][HTML] ACE2-independent alternative receptors for SARS-CoV-2

S Lim, M Zhang, TL Chang - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome-related coronavirus (SARS-CoV-2), the causative agent
of coronavirus disease 2019 (COVID-19), is highly contagious and remains a major public …

Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection

J Luan, Y Lu, X Jin, L Zhang - Biochemical and biophysical research …, 2020 - Elsevier
SARS-CoV-2 causes the recent global COVID-19 public health emergency. ACE2 is the
receptor for both SARS-CoV-2 and SARS-CoV. To predict the potential host range of SARS …