Diverse roles of macrophages in atherosclerosis: from inflammatory biology to biomarker discovery
T Gui, A Shimokado, Y Sun, T Akasaka… - Mediators of …, 2012 - Wiley Online Library
Cardiovascular disease, a leading cause of mortality in developed countries, is mainly
caused by atherosclerosis, a chronic inflammatory disease. Macrophages, which …
caused by atherosclerosis, a chronic inflammatory disease. Macrophages, which …
Macrophages heterogeneity in atherosclerosis–implications for therapy
HM Wilson - Journal of cellular and molecular medicine, 2010 - Wiley Online Library
Introduction• Current concepts in monocyte heterogeneity• Pro‐atherogenic role of plaque
macrophages• Anti‐atherogenic role of plaque macrophages• Macrophage heterogeneity …
macrophages• Anti‐atherogenic role of plaque macrophages• Macrophage heterogeneity …
Roles of macrophages in atherogenesis
Atherosclerosis is a chronic inflammatory disease that may ultimately lead to local
proteolysis, plaque rupture, and thrombotic vascular disease, resulting in myocardial …
proteolysis, plaque rupture, and thrombotic vascular disease, resulting in myocardial …
Macrophages and their role in atherosclerosis: pathophysiology and transcriptome analysis
YV Bobryshev, EA Ivanova… - BioMed research …, 2016 - Wiley Online Library
Atherosclerosis can be regarded as a chronic inflammatory state, in which macrophages
play different and important roles. Phagocytic proinflammatory cells populate growing …
play different and important roles. Phagocytic proinflammatory cells populate growing …
Vascular macrophages in atherosclerosis
Atherosclerosis is the main pathological basis for the occurrence of most cardiovascular
diseases, the leading global health threat, and a great burden for society. It has been well …
diseases, the leading global health threat, and a great burden for society. It has been well …
Macrophage phenotype and function in different stages of atherosclerosis
I Tabas, KE Bornfeldt - Circulation research, 2016 - Am Heart Assoc
The remarkable plasticity and plethora of biological functions performed by macrophages
have enticed scientists to study these cells in relation to atherosclerosis for> 50 years, and …
have enticed scientists to study these cells in relation to atherosclerosis for> 50 years, and …
Macrophages: promising targets for the treatment of atherosclerosis
HM Wilson, RN Barker, LP Erwig - Current vascular …, 2009 - ingentaconnect.com
Atherosclerosis is now recognised as a chronic inflammatory disease occurring within the
artery wall and ultimately responsible for myocardial infarction, stroke and peripheral …
artery wall and ultimately responsible for myocardial infarction, stroke and peripheral …
Changes in transcriptome of macrophages in atherosclerosis
DA Chistiakov, YV Bobryshev… - Journal of cellular and …, 2015 - Wiley Online Library
Macrophages display significant phenotypic heterogeneity. Two growth factors, macrophage
colony‐stimulating factor and chemokine (C‐X‐C motif) ligand 4, drive terminal …
colony‐stimulating factor and chemokine (C‐X‐C motif) ligand 4, drive terminal …
Macrophage biology in cardiovascular diseases
Macrophages have a key functional role in the pathogenesis of various cardiovascular
diseases, such as atherosclerosis and aortic aneurysms. Their accumulation within the …
diseases, such as atherosclerosis and aortic aneurysms. Their accumulation within the …
The role of monocytes and macrophages in human atherosclerosis, plaque neoangiogenesis, and atherothrombosis
Atherosclerosis is one of the leading causes of death and disability worldwide. It is a
complex disease characterized by lipid accumulation within the arterial wall, inflammation …
complex disease characterized by lipid accumulation within the arterial wall, inflammation …