Cardiovascular disease, a leading cause of mortality in developed countries, is mainly
caused by atherosclerosis, a chronic inflammatory disease. Macrophages, which …

Introduction• Current concepts in monocyte heterogeneity• Pro‐atherogenic role of plaque
macrophages• Anti‐atherogenic role of plaque macrophages• Macrophage heterogeneity …

Atherosclerosis is a chronic inflammatory disease that may ultimately lead to local
proteolysis, plaque rupture, and thrombotic vascular disease, resulting in myocardial …

Atherosclerosis can be regarded as a chronic inflammatory state, in which macrophages
play different and important roles. Phagocytic proinflammatory cells populate growing …

Atherosclerosis is the main pathological basis for the occurrence of most cardiovascular
diseases, the leading global health threat, and a great burden for society. It has been well …

The remarkable plasticity and plethora of biological functions performed by macrophages
have enticed scientists to study these cells in relation to atherosclerosis for> 50 years, and …

Atherosclerosis is now recognised as a chronic inflammatory disease occurring within the
artery wall and ultimately responsible for myocardial infarction, stroke and peripheral …

Macrophages display significant phenotypic heterogeneity. Two growth factors, macrophage
colony‐stimulating factor and chemokine (C‐X‐C motif) ligand 4, drive terminal …

Atherosclerosis is one of the leading causes of death and disability worldwide. It is a
complex disease characterized by lipid accumulation within the arterial wall, inflammation …

Macrophages have a key functional role in the pathogenesis of various cardiovascular
diseases, such as atherosclerosis and aortic aneurysms. Their accumulation within the …