The pathobiology of Aspergillus fumigatus

JP Latgé - Trends in microbiology, 2001 - cell.com
Aspergillus fumigatus is the most prevalent airborne fungal pathogen in developed
countries, and in immunocompromised patients causes a usually fatal invasive aspergillosis …

Aspergillus fumigatus: contours of an opportunistic human pathogen

A McCormick, J Loeffler, F Ebel - Cellular microbiology, 2010 - Wiley Online Library
Aspergillus fumigatus is currently the major air‐borne fungal pathogen. It is able to cause
several forms of disease in humans of which invasive aspergillosis is the most severe. The …

Aspergillus fumigatus and Aspergillosis

JP Latgé - Clinical microbiology reviews, 1999 - Am Soc Microbiol
Aspergillus fumigatus is one of the most ubiquitous of the airborne saprophytic fungi.
Humans and animals constantly inhale numerous conidia of this fungus. The conidia are …

[HTML][HTML] Aspergillus fumigatus—What Makes the Species a Ubiquitous Human Fungal Pathogen?

KJ Kwon-Chung, JA Sugui - PLoS pathogens, 2013 - journals.plos.org
Aspergillus fumigatus, the major cause of life threatening invasive aspergillosis (IA), is a
ubiquitous saprophytic fungus to which humans are exposed daily in most parts of the world …

Aspergillus fumigatus: Principles of Pathogenesis and Host Defense

TM Hohl, M Feldmesser - Eukaryotic cell, 2007 - Am Soc Microbiol
Aspergillus fumigatus is a ubiquitous saprophytic mold (67) that forms airborne spores
(conidia). Humans inhale, on average, hundreds of these infectious propagules daily. In …

Pathogenicity and virulence of Aspergillus fumigatus

K Earle, C Valero, DP Conn, G Vere, PC Cook… - Virulence, 2023 - Taylor & Francis
Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

[HTML][HTML] The innate immune response to Aspergillus fumigatus

V Balloy, M Chignard - Microbes and infection, 2009 - Elsevier
Despite the development of new treatments, the mortality due to invasive pulmonary
aspergillosis remains above 50%, reaching 95% in certain situations. The battle against …

Systemic fungal infections caused by Aspergillus species: epidemiology, infection process and virulence determinants

AA Brakhage - Current drug targets, 2005 - ingentaconnect.com
Infections with mould pathogens have emerged as an increasing risk faced by patients
under sustained immunosuppression. Species of the Aspergillus family account for most of …

The innate immune response to Aspergillus fumigatus at the alveolar surface

A Margalit, K Kavanagh - FEMS microbiology reviews, 2015 - academic.oup.com
Aspergillus fumigatus is an ubiquitous, saprophytic mould that forms and releases airborne
conidia which are inhaled by humans on a daily basis. When the immune system is …

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

TRT Dagenais, NP Keller - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Aspergillus species are globally ubiquitous saprophytes found in a variety of ecological
niches. Almost 200 species of aspergilli have been identified, less than 20 of which are …