[PDF][PDF] Genes and molecules involved in Aspergillus fumigatus virulence

A Rementeria, N López-Molina, A Ludwig… - Rev Iberoam …, 2005 - reviberoammicol.com
Aspergillus fumigatus causes a wide range of diseases that include mycotoxicosis, allergic
reactions and systemic diseases (invasive aspergillosis) with high mortality rates …

Aspergillosis: pathogenesis, clinical manifestations, and therapy

KA Marr, T Patterson, D Denning - Infectious Disease Clinics, 2002 - id.theclinics.com
Diseases caused by Aspergillus species are numerous, ranging from allergic
manifestations, to pulmonary saprophytic or locally destructive disease, to the almost …

Differences in pathogenicity and clinical syndromes due to Aspergillus fumigatus and Aspergillus flavus

AC Pasqualotto - Medical mycology, 2009 - academic.oup.com
Most of the information available about Aspergillus infections has originated from the study
of A. fumigatus, the most frequent species in the genus. This review aims to compare the …

Pathophysiology and immunology of allergic bronchopulmonary aspergillosis

RB Moss - Medical mycology, 2005 - Taylor & Francis
Allergic bronchopulmonary aspergillosis (ABPA) is a complication of persistent asthma and
cystic fibrosis (CF), diseases in part characterized by excessive viscous mucus and …

Aspergillus fumigatus: virulence genes in a street-smart mold

DS Askew - Current opinion in microbiology, 2008 - Elsevier
Infections with the filamentous fungus Aspergillus fumigatus are among the most devastating
of the systemic mycoses. Unlike most primary pathogens, which possess virulence traits that …

Biofilm formation by Aspergillus fumigatus

S Kaur, S Singh - Medical mycology, 2014 - academic.oup.com
Aspergillus fumigatus is a well adapted, opportunistic fungus that causes a severe and
commonly fatal disease, invasive pulmonary aspergillosis (IPA), in highly …

Putative virulence factors of Aspergillus fumigatus

Tomee, Kauffman - Clinical & Experimental Allergy, 2000 - Wiley Online Library
Various putative virulence factors of Aspergillus fumigatus have been studied over the past
decades. A. fumigatus gliotoxin is a potent inhibitor of the mucociliary system. Several fungal …

Molecular Epidemiology of Aspergillus fumigatus Isolates Recovered from Water, Air, and Patients Shows Two Clusters of Genetically Distinct Strains

A Warris, CHW Klaassen, JFGM Meis… - Journal of Clinical …, 2003 - Am Soc Microbiol
There has been an increase in data suggesting that besides air, hospital water is a potential
source of transmission of filamentous fungi, and in particular Aspergillus fumigatus …

Aspergillus fumigatus Variant with Decreased Susceptibility to Multiple Antifungals

SA Balajee, M Weaver, A Imhof… - Antimicrobial agents …, 2004 - Am Soc Microbiol
Isolates of Aspergillus fumigatus that demonstrate resistance to itraconazole (ITZ) have been
described previously; however, the prevalence and clinical significance of ITZ resistance are …

Virulence of Aspergillus fumigatus double mutants lacking restriction and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis

JM Smith, CM Tang, S Van Noorden… - Infection and …, 1994 - Am Soc Microbiol
To investigate the pathogenicity of Aspergillus fumigatus mutants lacking putative virulence
factors, we have developed a new murine model of invasive pulmonary aspergillosis based …